moaC protein (Isosphaera pallida) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

moaC

GTP cyclohydrolase subunit MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (174 aa)

Predicted Functional Partners:

moaA

0.999

Isop_1676

0.990

Isop_3005

0.980

Isop_1255

0.884

Isop_3431

0.823

Isop_1559

0.821

Isop_2632

0.783

Isop_1375

0.754

Isop_0271

0.660

cmk

0.581

Your Current Organism:

Isosphaera pallida

NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Isop_0271	moaC	Isop_0271	Isop_0270	Polyprenyl synthetase; COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: plm:Plim_0149 trans-hexaprenyltranstransferase; PFAM: Polyprenyl synthetase; SPTR: Trans-hexaprenyltranstransferase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.	GTP cyclohydrolase subunit MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.	0.660
Isop_1255	Isop_1559	Isop_1255	Isop_1559	Molybdopterin molybdochelatase; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.	Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.	0.932
Isop_1255	Isop_1676	Isop_1255	Isop_1676	Molybdopterin molybdochelatase; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.	COGs: COG0521 Molybdopterin biosynthesis protein; InterPro IPR008284: IPR020817: IPR001453; KEGG: pca:Pcar_2074 molybdenum cofactor biosynthesis protein; PFAM: molybdopterin binding domain; SPTR: Molybdenum cofactor biosynthesis mog; TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: Probable molybdopterin binding domain; TIGRFAM: molybdenum cofactor synthesis domain.	0.996
Isop_1255	Isop_2632	Isop_1255	Isop_2632	Molybdopterin molybdochelatase; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.	Molybdopterin converting factor, subunit 1; InterPro IPR003749: IPR010034; KEGG: psl:Psta_2343 thiamineS protein; PFAM: thiamineS protein; SPTR: ThiamineS protein; TIGRFAM: molybdopterin converting factor, subunit 1; PFAM: ThiS family; TIGRFAM: molybdopterin converting factor, subunit 1, non-archaeal.	0.420
Isop_1255	Isop_3005	Isop_1255	Isop_3005	Molybdopterin molybdochelatase; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.	COGs: COG0314 Molybdopterin converting factor large subunit; InterPro IPR003448; KEGG: plm:Plim_0864 molybdopterin biosynthesis MoaE protein; PFAM: molybdopterin biosynthesis MoaE protein; SPTR: Molybdopterin converting factor (Subunit 2); PFAM: MoaE protein.	0.807
Isop_1255	Isop_3431	Isop_1255	Isop_3431	Molybdopterin molybdochelatase; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.	Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.	0.933
Isop_1255	moaA	Isop_1255	Isop_3006	Molybdopterin molybdochelatase; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.	GTP cyclohydrolase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.	0.913
Isop_1255	moaC	Isop_1255	Isop_0270	Molybdopterin molybdochelatase; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.	GTP cyclohydrolase subunit MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.	0.884
Isop_1375	Isop_1676	Isop_1375	Isop_1676	thiamineS protein; InterPro IPR003749; KEGG: tfu:Tfu_2369 hypothetical protein; PFAM: thiamineS protein; SPTR: Putative uncharacterized protein; manually curated; PFAM: ThiS family.	COGs: COG0521 Molybdopterin biosynthesis protein; InterPro IPR008284: IPR020817: IPR001453; KEGG: pca:Pcar_2074 molybdenum cofactor biosynthesis protein; PFAM: molybdopterin binding domain; SPTR: Molybdenum cofactor biosynthesis mog; TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: Probable molybdopterin binding domain; TIGRFAM: molybdenum cofactor synthesis domain.	0.513
Isop_1375	Isop_2632	Isop_1375	Isop_2632	thiamineS protein; InterPro IPR003749; KEGG: tfu:Tfu_2369 hypothetical protein; PFAM: thiamineS protein; SPTR: Putative uncharacterized protein; manually curated; PFAM: ThiS family.	Molybdopterin converting factor, subunit 1; InterPro IPR003749: IPR010034; KEGG: psl:Psta_2343 thiamineS protein; PFAM: thiamineS protein; SPTR: ThiamineS protein; TIGRFAM: molybdopterin converting factor, subunit 1; PFAM: ThiS family; TIGRFAM: molybdopterin converting factor, subunit 1, non-archaeal.	0.912
Isop_1375	Isop_3005	Isop_1375	Isop_3005	thiamineS protein; InterPro IPR003749; KEGG: tfu:Tfu_2369 hypothetical protein; PFAM: thiamineS protein; SPTR: Putative uncharacterized protein; manually curated; PFAM: ThiS family.	COGs: COG0314 Molybdopterin converting factor large subunit; InterPro IPR003448; KEGG: plm:Plim_0864 molybdopterin biosynthesis MoaE protein; PFAM: molybdopterin biosynthesis MoaE protein; SPTR: Molybdopterin converting factor (Subunit 2); PFAM: MoaE protein.	0.929
Isop_1375	moaA	Isop_1375	Isop_3006	thiamineS protein; InterPro IPR003749; KEGG: tfu:Tfu_2369 hypothetical protein; PFAM: thiamineS protein; SPTR: Putative uncharacterized protein; manually curated; PFAM: ThiS family.	GTP cyclohydrolase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.	0.623
Isop_1375	moaC	Isop_1375	Isop_0270	thiamineS protein; InterPro IPR003749; KEGG: tfu:Tfu_2369 hypothetical protein; PFAM: thiamineS protein; SPTR: Putative uncharacterized protein; manually curated; PFAM: ThiS family.	GTP cyclohydrolase subunit MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.	0.754
Isop_1559	Isop_1255	Isop_1559	Isop_1255	Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.	Molybdopterin molybdochelatase; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.	0.932
Isop_1559	Isop_1676	Isop_1559	Isop_1676	Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.	COGs: COG0521 Molybdopterin biosynthesis protein; InterPro IPR008284: IPR020817: IPR001453; KEGG: pca:Pcar_2074 molybdenum cofactor biosynthesis protein; PFAM: molybdopterin binding domain; SPTR: Molybdenum cofactor biosynthesis mog; TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: Probable molybdopterin binding domain; TIGRFAM: molybdenum cofactor synthesis domain.	0.996
Isop_1559	Isop_3005	Isop_1559	Isop_3005	Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.	COGs: COG0314 Molybdopterin converting factor large subunit; InterPro IPR003448; KEGG: plm:Plim_0864 molybdopterin biosynthesis MoaE protein; PFAM: molybdopterin biosynthesis MoaE protein; SPTR: Molybdopterin converting factor (Subunit 2); PFAM: MoaE protein.	0.802
Isop_1559	Isop_3431	Isop_1559	Isop_3431	Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.	Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.	0.927
Isop_1559	moaA	Isop_1559	Isop_3006	Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.	GTP cyclohydrolase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.	0.850
Isop_1559	moaC	Isop_1559	Isop_0270	Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.	GTP cyclohydrolase subunit MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.	0.821
Isop_1676	Isop_1255	Isop_1676	Isop_1255	COGs: COG0521 Molybdopterin biosynthesis protein; InterPro IPR008284: IPR020817: IPR001453; KEGG: pca:Pcar_2074 molybdenum cofactor biosynthesis protein; PFAM: molybdopterin binding domain; SPTR: Molybdenum cofactor biosynthesis mog; TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: Probable molybdopterin binding domain; TIGRFAM: molybdenum cofactor synthesis domain.	Molybdopterin molybdochelatase; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.	0.996

page 1 of 4

Server load: low (20%) [HD]

Permalink

Network

Neighborhood

Experiments

Fusion

Databases

Co-occurrence

Textmining

Co-expression

© STRING Consortium 2026

Credits

Access

Info

About