STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Isop_0280Beta-lactamase domain-containing protein; COGs: COG0491 Zn-dependent hydrolase including glyoxylase; KEGG: pvi:Cvib_1640 beta-lactamase domain-containing protein; SPTR: Beta-lactamase domain protein; PFAM: Metallo-beta-lactamase superfamily; Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family. (217 aa)    
Predicted Functional Partners:
Isop_0281
InterPro IPR011444: IPR010869; KEGG: psl:Psta_3333 protein of unknown function DUF1501; PFAM: protein of unknown function DUF1501; protein of unknown function DUF1549; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1501); Protein of unknown function (DUF1549).
       0.773
Isop_2700
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR001763: IPR013027: IPR004099; KEGG: psl:Psta_1619 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; Rhodanese domain protein; SMART: Rhodanese domain protein; SPTR: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Rhodanese-like domain; Pyridine nucleotide-disul [...]
  
 0.687
Isop_0282
KEGG: min:Minf_1147 Zn-dependent hydrolase, glyoxylase family; SPTR: Putative uncharacterized protein.
       0.558
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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