Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Isop_0300Esterase; COGs: COG2382 Enterochelin esterase; InterPro IPR004193: IPR000801; KEGG: sli:Slin_1254 putative esterase; PFAM: esterase; glycoside hydrolase family 13 domain protein; SPTR: Putative esterase; PFAM: Carbohydrate-binding module 48 (Isoamylase N-terminal domain); Putative esterase. (387 aa)    
Predicted Functional Partners:
Isop_3649
COGs: COG0657 Esterase/lipase; KEGG: psl:Psta_3524 exported endo-1,4-beta-xylanase; SPTR: Xylanase; PFAM: Prolyl oligopeptidase family; alpha/beta hydrolase fold.
  
     0.584
Isop_0681
Glycoside hydrolase family 10; COGs: COG3693 Beta-1 4-xylanase; KEGG: plm:Plim_3847 glycoside hydrolase family 10; SPTR: Glycoside hydrolase family 10.
   
   0.572
Isop_3281
InterPro IPR012577; KEGG: psl:Psta_4030 NIPSNAP family containing protein; PFAM: NIPSNAP family containing protein; SPTR: NIPSNAP family containing protein; PFAM: NIPSNAP.
  
     0.521
Isop_2633
Peptidase S9B dipeptidylpeptidase IV domain protein; COGs: COG1506 Dipeptidyl aminopeptidase/acylaminoacyl-peptidase; InterPro IPR002469; KEGG: gau:GAU_3554 putative dipeptidyl peptidase; PFAM: peptidase S9B dipeptidylpeptidase IV domain protein; SPTR: Peptidase S9 prolyl oligopeptidase active site domain protein; PFAM: Prolyl oligopeptidase family; Dipeptidyl peptidase IV (DPP IV) N-terminal region.
  
     0.483
Isop_2611
InterPro IPR017969: IPR010496; KEGG: psl:Psta_2463 protein of unknown function DUF1080; PFAM: protein of unknown function DUF1080; SPTR: Putative uncharacterized protein; PFAM: Domain of Unknown Function (DUF1080).
  
     0.449
Isop_0299
Protein of unknown function DUF486; COGs: COG3169 conserved hypothetical protein; InterPro IPR007437; KEGG: dia:Dtpsy_2708 protein of unknown function DUF486; PFAM: protein of unknown function DUF486; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function, DUF486.
       0.447
Isop_2477
Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR017909: IPR000683: IPR006311; KEGG: plm:Plim_0037 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase family, C-terminal alpha/beta domain; Oxidoreductase family, NAD-binding Rossmann fold; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence.
  
     0.441
Isop_2725
KEGG: ote:Oter_0116 putative acetyl xylan esterase; SPTR: Probable acetyl xylan esterase.
  
     0.435
Isop_2013
COGs: COG3386 Gluconolactonase; InterPro IPR000801: IPR013658: IPR005511; KEGG: plm:Plim_2162 SMP-30/gluconolaconase/LRE domain protein; PFAM: SMP-30/Gluconolaconase/LRE-like region-containing protein; esterase; SPTR: SMP-30/Gluconolaconase/LRE domain protein; PFAM: SMP-30/Gluconolaconase/LRE-like region; Putative esterase.
  
     0.425
Isop_0606
InterPro IPR010496; KEGG: tra:Trad_1254 protein of unknown function DUF1080; PFAM: protein of unknown function DUF1080; SPTR: Putative uncharacterized protein; PFAM: Domain of Unknown Function (DUF1080).
  
     0.420
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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