STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Isop_0303Appr-1-p processing domain protein; COGs: COG2110 phosphatase homologous to the C-terminal domain of histone macroH2A1; InterPro IPR002589; KEGG: rba:RB4366 hypothetical protein; PFAM: Appr-1-p processing domain protein; SMART: Appr-1-p processing domain protein; SPTR: Putative uncharacterized protein; PFAM: Macro domain. (165 aa)    
Predicted Functional Partners:
Isop_0302
Sulfatase; COGs: COG3119 Arylsulfatase A; InterPro IPR000917; KEGG: plm:Plim_0571 sulfatase; PFAM: sulfatase; SPTR: Sulfatase; PFAM: Sulfatase.
       0.741
Isop_0301
Hypothetical protein; KEGG: psl:Psta_3458 methyltransferase type 11; SPTR: Methyltransferase type 11; PFAM: DsrE/DsrF-like family.
       0.648
rplK
LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
    
   0.623
rplX
LSU ribosomal protein L24P; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
    
   0.623
rplC
LSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
    
   0.598
rplB
LSU ribosomal protein L2P; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
    
   0.598
rplT
LSU ribosomal protein L20P; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.
   
   0.586
Isop_0256
Mandelate racemase/muconate lactonizing protein; COGs: COG4948 L-alanine-DL-glutamate epimerase; InterPro IPR013342; KEGG: rba:RB10855 muconate cycloisomerase I; PFAM: Mandelate racemase/muconate lactonizing protein; SPTR: Muconate cycloisomerase I; PFAM: Mandelate racemase / muconate lactonizing enzyme, C-terminal domain.
   
   0.575
Isop_0509
KEGG: plm:Plim_2156 transmembrane prediction; SPTR: Putative uncharacterized protein; Belongs to the mandelate racemase/muconate lactonizing enzyme family.
   
   0.575
menC
O-succinylbenzoate synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB).
   
   0.575
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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