STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_0306COGs: COG0405 Gamma-glutamyltransferase; InterPro IPR000101; KEGG: gau:GAU_2335 gamma-glutamyltranspeptidase precursor; PFAM: gamma-glutamyltranspeptidase; PRIAM: Gamma-glutamyltransferase; SPTR: Gamma-glutamyltranspeptidase; TIGRFAM: gamma-glutamyltransferase; PFAM: Gamma-glutamyltranspeptidase; TIGRFAM: gamma-glutamyltranspeptidase. (618 aa)    
Predicted Functional Partners:
Isop_2261
COGs: COG0405 Gamma-glutamyltransferase; InterPro IPR000101; KEGG: aba:Acid345_3078 gamma-glutamyltransferase 2; PFAM: gamma-glutamyltranspeptidase; PRIAM: Gamma-glutamyltransferase; SPTR: Gamma-glutamyltransferase 2. Threonine peptidase. MEROPS family T03; PFAM: Gamma-glutamyltranspeptidase; TIGRFAM: gamma-glutamyltranspeptidase.
  
  
 
0.929
gshB
COGs: COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase); InterPro IPR011761: IPR006284: IPR004215: IPR004218; KEGG: scl:sce7568 glutathione synthetase; PFAM: glutathione synthetase ATP-binding; glutathione synthetase domain protein; PRIAM: Glutathione synthase; SPTR: Glutathione synthetase; TIGRFAM: glutathione synthetase; PFAM: Prokaryotic glutathione synthetase, N-terminal domain; Prokaryotic glutathione synthetase, ATP-grasp domain; TIGRFAM: glutathione synthetase, prokaryotic; Belongs to the prokaryotic GSH synthase family.
  
  
 0.920
Isop_1457
Glutamate--cysteine ligase; COGs: COG3572 Gamma-glutamylcysteine synthetase; InterPro IPR006336; KEGG: nml:Namu_1082 glutamate/cysteine ligase family protein; PFAM: glutamate--cysteine ligase GCS2; PRIAM: Glutamate--cysteine ligase; SPTR: Glutamate/cysteine ligase family protein; PFAM: Glutamate-cysteine ligase family 2(GCS2); TIGRFAM: glutamate--cysteine ligase, plant type.
  
  
  0.914
pepA
Peptidase M17 leucyl aminopeptidase domain protein; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
     
 0.912
Isop_2902
Peroxiredoxin; COGs: COG0386 Glutathione peroxidase; InterPro IPR000889; KEGG: sus:Acid_7250 glutathione peroxidase; PFAM: glutathione peroxidase; PRIAM: Peroxiredoxin; SPTR: Glutathione peroxidase; PFAM: Glutathione peroxidase; Belongs to the glutathione peroxidase family.
     
 0.912
Isop_0121
Glutamate--cysteine ligase GCS2; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
  
 
 0.911
Isop_1001
InterPro IPR001129: IPR001446; KEGG: gvi:glr3057 glutathione S-transferase; PFAM: membrane-associated protein in eicosanoid and glutathione metabolism (MAPEG); SPTR: Glr3057 protein; PFAM: MAPEG family.
  
 
  0.905
Isop_1222
COGs: COG1984 Allophanate hydrolase subunit 2; InterPro IPR003778; KEGG: mca:MCA0477 allophanate hydrolase, subunit 2; PFAM: Allophanate hydrolase subunit 2; SMART: Allophanate hydrolase subunit 2; SPTR: Allophanate hydrolase, subunit 2; PFAM: Allophanate hydrolase subunit 2.
     
  0.900
Isop_1379
COGs: COG0308 Aminopeptidase N; InterPro IPR014782; KEGG: mxa:MXAN_0644 M1 family peptidase; PFAM: Peptidase M1 membrane alanine aminopeptidase; SPTR: Peptidase, M1 (Aminopeptidase N) family; PFAM: Peptidase family M1.
     
  0.900
Isop_2214
Glutamate synthase (NADH) large subunit; COGs: COG0069 Glutamate synthase domain 2; InterProIPR000583: IPR006982: IPR002932: IPR002489: IPR 017932; KEGG: ttr:Tter_0474 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: Glutamate synthase (Ferredoxin); PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
     
 0.879
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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