STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_0315Radical SAM domain protein; COGs: COG1032 Fe-S oxidoreductase; InterPro IPR007197: IPR006638; KEGG: rba:RB5334 Fe-S oxidoreductase; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Fe-S oxidoreductase; PFAM: Radical SAM superfamily. (598 aa)    
Predicted Functional Partners:
Isop_1106
Protein of unknown function DUF2344; COGs: COG5011 conserved hypothetical protein; InterPro IPR018768; KEGG: afw:Anae109_0737 radical SAM domain-containing protein; PFAM: Protein of unknown function DUF2344; SPTR: Radical SAM domain protein; PFAM: Uncharacterized protein conserved in bacteria (DUF2344).
 
    0.785
Isop_2218
4-vinyl reductase 4VR; InterPro IPR004096; KEGG: cyp:PCC8801_1056 4-vinyl reductase 4VR; PFAM: 4-vinyl reductase 4VR; SPTR: 4-vinyl reductase 4VR; PFAM: V4R domain.
  
  
 0.645
Isop_2221
4-vinyl reductase 4VR; COGs: COG1719 hydrocarbon binding protein (contains V4R domain); InterPro IPR004096; KEGG: tel:tll0856 hypothetical protein; PFAM: 4-vinyl reductase 4VR; SPTR: 4-vinyl reductase 4VR; PFAM: V4R domain.
  
  
 0.645
menG
Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
  
    0.522
Isop_0316
KEGG: rrs:RoseRS_1412 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.520
Isop_0314
Redoxin domain protein; InterPro IPR013740: IPR009056: IPR017936; KEGG: psl:Psta_2862 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen; PFAM: Redoxin domain protein; SPTR: Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; PFAM: Copper type II ascorbate-dependent monooxygenase, C-terminal domain; Redoxin.
       0.401
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.