STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
Isop_0323Glycoside hydrolase family 5; COGs: COG2730 Endoglucanase; InterPro IPR001547: IPR018087; KEGG: trq:TRQ2_1074 glycoside hydrolase family protein; PFAM: glycoside hydrolase family 5; SPTR: Glycoside hydrolase family 5; PFAM: Cellulase (glycosyl hydrolase family 5); Belongs to the glycosyl hydrolase 5 (cellulase A) family. (350 aa)    
Predicted Functional Partners:
Isop_0321
HAD-superfamily hydrolase, subfamily IA, variant 1; COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR005834: IPR006439; KEGG: plm:Plim_4115 HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: Putative uncharacterized protein; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E.
       0.668
tsaD
O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
       0.668
Isop_0324
Peptidase M24; COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR000994; KEGG: psl:Psta_2870 peptidase M24; PFAM: peptidase M24; SPTR: Peptidase M24; PFAM: Metallopeptidase family M24.
       0.601
Isop_0089
N-acylglucosamine 2-epimerase; COGs: COG1331 Highly conserved protein containing a thioredoxin domain; InterPro IPR010819; KEGG: bts:Btus_0399 protein of unknown function DUF255; PFAM: N-acylglucosamine 2-epimerase; SPTR: Putative uncharacterized protein; PFAM: N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase); Protein of unknown function, DUF255.
   
 
 0.599
Isop_0491
Protein of unknown function DUF255; COGs: COG1331 Highly conserved protein containing a thioredoxin domain; KEGG: psl:Psta_0467 protein of unknown function DUF255; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function, DUF255.
   
 
 0.599
Isop_1117
Glycoside hydrolase family 9; InterPro IPR001701; KEGG: tfu:Tfu_2176 endoglucanase; PFAM: glycoside hydrolase family 9; SPTR: Endoglucanase. Glycosyl Hydrolase family 9; PFAM: Glycosyl hydrolase family 9.
 
 
 0.429
Isop_1978
Sialate O-acetylesterase; InterPro IPR005181; KEGG: rba:RB10048 sialic acid-specific 9-O-acetylesterase; PFAM: protein of unknown function DUF303 acetylesterase; PRIAM: Sialate O-acetylesterase; SPTR: Sialic acid-specific 9-O-acetylesterase; PFAM: Domain of unknown function (DUF303).
 
 
 
 0.426
Isop_1608
Carbohydrate binding family 6; InterProIPR003961: IPR005084: IPR018247: IPR006626: IPR 006584: IPR011459; KEGG: sco:SCO7170 secreted sugar hydrolase; PFAM: Carbohydrate binding family 6; protein of unknown function DUF1565; Fibronectin type III domain protein; SMART: cellulose binding type IV; Parallel beta-helix repeat; Fibronectin type III domain protein; SPTR: Carbohydrate binding family 6; PFAM: Carbohydrate binding module (family 6); Fibronectin type III domain.
  
     0.425
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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