STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_0332tRNA synthetase class II (G H P and S); InterPro IPR002314: IPR000408: IPR006195; KEGG: scl:sce6565 hypothetical protein; PFAM: tRNA synthetase class II (G H P and S); SPTR: SerS1 protein; PFAM: tRNA synthetase class II core domain (G, H, P, S and T). (417 aa)    
Predicted Functional Partners:
Isop_0330
Hypothetical protein; COGs: COG0110 Acetyltransferase (isoleucine patch superfamily); InterPro IPR001451: IPR018357; KEGG: scl:sce6563 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Bacterial transferase hexapeptide (three repeats).
    0.881
Isop_0331
Phosphopantetheine-binding protein; InterPro IPR006163: IPR006162: IPR009081; KEGG: scl:sce6564 hypothetical protein; PFAM: phosphopantetheine-binding; SPTR: Putative uncharacterized protein; manually curated; PFAM: Phosphopantetheine attachment site.
   
   0.783
Isop_0333
Hypothetical protein; InterPro IPR000182; KEGG: scl:sce6566 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.773
Isop_2115
COGs: COG2191 Formylmethanofuran dehydrogenase subunit E; InterPro IPR003814; KEGG: cyb:CYB_0846 hypothetical protein; PFAM: formylmethanofuran dehydrogenase subunit E region; SPTR: Conserved domain protein; PFAM: FmdE, Molybdenum formylmethanofuran dehydrogenase operon.
  
     0.659
Isop_0328
Phosphopantetheine-binding protein; InterPro IPR006163: IPR009081; KEGG: drt:Dret_1416 acyl carrier protein; PFAM: phosphopantetheine-binding; SPTR: Phosphopantetheine-binding; PFAM: Phosphopantetheine attachment site; TIGRFAM: acyl carrier protein.
   
   0.626
Isop_2054
Protein of unknown function DUF37; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.
  
    0.620
Isop_2003
KR domain protein; COGs: COG3321 Polyketide synthase modules and related protein; InterProIPR014031: IPR014043: IPR006163: IPR013968: IPR 009081; KEGG: glo:Glov_2267 polyketide-type polyunsaturated fatty acid synthase PfaA; PFAM: KR domain protein; Beta-ketoacyl synthase; Acyl transferase; phosphopantetheine-binding; SPTR: Polyketide-type polyunsaturated fatty acid synthase PfaA; PFAM: Acyl transferase domain; Phosphopantetheine attachment site; KR domain; Beta-ketoacyl synthase, C-terminal domain; TIGRFAM: acyl carrier protein.
   
   0.584
argS
COGs: COG0018 Arginyl-tRNA synthetase; InterProIPR001278: IPR015945: IPR005148: IPR008909: IPR 001800: IPR001412; KEGG: psl:Psta_0209 arginyl-tRNA synthetase; PFAM: Arginyl-tRNA synthetase, class Ic, core; arginyl tRNA synthetase domain protein; DALR anticodon binding domain protein; PRIAM: Arginine--tRNA ligase; SPTR: Arginyl-tRNA synthetase; TIGRFAM: arginyl-tRNA synthetase; PFAM: DALR anticodon binding domain; Arginyl tRNA synthetase N terminal domain; tRNA synthetases class I (R); TIGRFAM: arginyl-tRNA synthetase.
  
 
 0.548
valS
valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
   
  
 0.533
glyQS
glycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly). Belongs to the class-II aminoacyl-tRNA synthetase family.
   
  
 0.508
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.