Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_0413Protein of unknown function DUF58; COGs: COG1721 conserved hypothetical protein (some members contain a von Willebrand factor type A (vWA) domain); InterPro IPR002881; KEGG: psl:Psta_1558 von Willebrand factor type A; PFAM: protein of unknown function DUF58; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function DUF58. (303 aa)    
Predicted Functional Partners:
Isop_0414
InterPro IPR011933; KEGG: psl:Psta_0478 hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: conserved hypothetical protein; PFAM: Aerotolerance regulator N-terminal; TIGRFAM: N-terminal double-transmembrane domain.
 
    0.868
Isop_0412
ATPase associated with various cellular activities AAA_3; COGs: COG0714 MoxR-like ATPase; InterPro IPR011703: IPR003593: IPR016366; KEGG: psl:Psta_1557 ATPase associated with various cellular activities AAA_3; PFAM: ATPase associated with various cellular activities AAA_3; SMART: AAA ATPase; SPTR: MoxR protein; PFAM: ATPase family associated with various cellular activities (AAA).
 
    0.859
Isop_0415
Protein of unknown function DUF1355; InterPro IPR010768: IPR002035; KEGG: plm:Plim_2313 hypothetical protein; PFAM: protein of unknown function DUF1355; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1355).
 
     0.817
Isop_1531
Von Willebrand factor type A; InterPro IPR002035: IPR013026; KEGG: dma:DMR_35140 hypothetical protein; PFAM: von Willebrand factor type A; SMART: von Willebrand factor type A; SPTR: Tetratricopeptide TPR_2 repeat protein; manually curated; PFAM: von Willebrand factor type A domain.
 
  
 0.789
Isop_1975
InterPro IPR002035; KEGG: srm:SRM_02789 von Willebrand factor type A domain protein; PFAM: von Willebrand factor type A; SMART: von Willebrand factor type A; SPTR: von Willebrand factor type A domain protein; PFAM: von Willebrand factor type A domain.
 
    0.760
Isop_3542
Conserved hypothetical protein; InterPro IPR011933: IPR002035; KEGG: psl:Psta_2914 hypothetical protein; PFAM: von Willebrand factor type A; SMART: von Willebrand factor type A; SPTR: Putative uncharacterized protein; TIGRFAM: conserved hypothetical protein; PFAM: von Willebrand factor type A domain; Aerotolerance regulator N-terminal; CARDB; TIGRFAM: N-terminal double-transmembrane domain.
 
    0.720
Isop_3570
Von Willebrand factor type A; InterPro IPR002035; KEGG: cte:CT2278 hypothetical protein; PFAM: von Willebrand factor type A; SMART: von Willebrand factor type A; SPTR: Putative uncharacterized protein; PFAM: von Willebrand factor type A domain.
 
    0.716
Isop_3544
ATPase associated with various cellular activities AAA_3; COGs: COG0714 MoxR-like ATPase; InterPro IPR016366: IPR011703; KEGG: psl:Psta_2916 ATPase associated with various cellular activities AAA_3; PFAM: ATPase associated with various cellular activities AAA_3; SPTR: Putative uncharacterized protein; PFAM: ATPase family associated with various cellular activities (AAA).
 
    0.710
Isop_3540
Hypothetical protein; KEGG: srm:SRM_02025 conserved hypothetical protein, membrane; SPTR: Putative uncharacterized protein.
  
     0.580
Isop_3170
KEGG: plm:Plim_2314 hypothetical protein; SPTR: Putative uncharacterized protein.
 
     0.540
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.