STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
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[Homology]
Score
Isop_0421GAF modulated sigma54 specific transcriptional regulator, Fis family; COGs: COG3284 Transcriptional activator of acetoin/glycerol metabolism; InterProIPR003018: IPR002078: IPR002197: IPR003593: IPR 020441; KEGG: afw:Anae109_3045 fis family GAF modulated sigma54 specific transcriptional regulator; PFAM: sigma-54 factor interaction domain-containing protein; GAF domain protein; helix-turn-helix Fis-type; SMART: AAA ATPase; SPTR: GAF modulated sigma54 specific transcriptional regulator, Fis family; PFAM: Bacterial regulatory protein, Fis family; Sigma-54 interaction domain. (763 aa)    
Predicted Functional Partners:
Isop_2995
COGs: COG1508 DNA-directed RNA polymerase specialized sigma subunit sigma54 homolog; InterPro IPR000394: IPR007046: IPR007634; KEGG: psl:Psta_2523 RNA polymerase, sigma 54 subunit, RpoN; PFAM: sigma-54 DNA-binding domain protein; sigma-54 factor core-binding region; sigma-54 factor; SPTR: RNA polymerase, sigma 54 subunit, RpoN; TIGRFAM: RNA polymerase sigma-54 factor, RpoN; PFAM: Sigma-54 factor, Activator interacting domain (AID); Sigma-54 factor, core binding domain; Sigma-54, DNA binding domain; TIGRFAM: RNA polymerase sigma-54 factor.
 
  
 0.810
rbsA
Monosaccharide ABC transporter ATP-binding protein, CUT2 family; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.
   
  
 0.417
Isop_1747
COGs: COG1966 Carbon starvation protein predicted membrane protein; InterPro IPR003706; KEGG: kra:Krad_4167 carbon starvation protein CstA; PFAM: carbon starvation protein CstA; SPTR: Carbon starvation protein CstA; PFAM: Carbon starvation protein CstA.
  
    0.401
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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