STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-expression
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[Homology]
Score
Isop_0422Alcohol dehydrogenase GroES domain protein; COGs: COG1064 Zn-dependent alcohol dehydrogenase; InterPro IPR013154: IPR013149: IPR002328; KEGG: rca:Rcas_4434 alcohol dehydrogenase; PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; SPTR: Alcohol dehydrogenase GroES domain protein; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase. (339 aa)    
Predicted Functional Partners:
Isop_1288
COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590: IPR016160: IPR001261; KEGG: plm:Plim_1868 retinal dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: Retinal dehydrogenase; PFAM: Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family.
  
 0.917
Isop_0941
COGs: COG1454 Alcohol dehydrogenase class IV; InterPro IPR001670: IPR017972; KEGG: reu:Reut_C6426 iron-containing alcohol dehydrogenase; PFAM: iron-containing alcohol dehydrogenase; SPTR: Iron-containing alcohol dehydrogenase; PFAM: Iron-containing alcohol dehydrogenase.
  
 
 0.820
Isop_2152
Alcohol dehydrogenase zinc-binding domain protein; COGs: COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductase; InterPro IPR018130: IPR013154: IPR013149; KEGG: gbe:GbCGDNIH1_0098 alcohol dehydrogenase; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; SPTR: Alcohol dehydrogenase; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase.
 
  
 0.687
leuC
3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
    
 
 0.620
Isop_0423
COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590: IPR016160; KEGG: aba:Acid345_1381 aldehyde dehydrogenase (acceptor); PFAM: Aldehyde Dehydrogenase; SPTR: Aldehyde dehydrogenase (Acceptor); PFAM: Aldehyde dehydrogenase family.
  
 
 0.559
Isop_3279
Alcohol dehydrogenase GroES domain protein; COGs: COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR013154: IPR001327; KEGG: chl:Chy400_0036 alcohol dehydrogenase GroES domain protein; PFAM: Alcohol dehydrogenase GroES domain protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Alcohol dehydrogenase GroES domain protein; PFAM: Alcohol dehydrogenase GroES-like domain.
 
 
0.438
Isop_3650
Phosphonate catabolism associated alcohol dehydrogenase; COGs: COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR013154: IPR013149: IPR017743; KEGG: psl:Psta_3166 phosphonate catabolism associated alcohol dehydrogenase; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; SPTR: Phosphonate catabolism associated alcohol dehydrogenase; TIGRFAM: phosphonate catabolism associated alcohol dehydrogenase; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; TIGRFAM: putative phosphonate cat [...]
 
 
0.430
Isop_3158
Cyclic nucleotide-binding protein; COGs: COG3383 Uncharacterized anaerobic dehydrogenase; InterProIPR017900: IPR018528: IPR018488: IPR002373: IPR 000595: IPR001041: IPR017896; KEGG: sus:Acid_4310 cyclic nucleotide-binding protein; PFAM: cyclic nucleotide-binding; ferredoxin; SMART: cyclic nucleotide-binding; SPTR: Cyclic nucleotide-binding protein; PFAM: Cyclic nucleotide-binding domain.
  
  
 0.405
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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