STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
psuGIndigoidine synthase A family protein; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family. (325 aa)    
Predicted Functional Partners:
Isop_1215
COGs: COG0035 Uracil phosphoribosyltransferase; InterPro IPR005765: IPR000836; KEGG: ttr:Tter_1755 uracil phosphoribosyltransferase; PFAM: phosphoribosyltransferase; SPTR: Uracil phosphoribosyltransferase; TIGRFAM: uracil phosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: uracil phosphoribosyltransferase; Belongs to the UPRTase family.
    
  0.905
Isop_2999
COGs: COG0213 Thymidine phosphorylase; InterProIPR017872: IPR017459: IPR000312: IPR013102: IPR 000053: IPR018090; KEGG: ank:AnaeK_0651 pyrimidine-nucleoside phosphorylase; PFAM: glycosyl transferase family 3; Glycosyl transferase, family 3-like; Pyrimidine nucleoside phosphorylase domain; PRIAM: Thymidine phosphorylase; SPTR: Pyrimidine-nucleoside phosphorylase; TIGRFAM: pyrimidine-nucleoside phosphorylase; PFAM: Pyrimidine nucleoside phosphorylase C-terminal domain; Glycosyl transferase family, a/b domain; Glycosyl transferase family, helical bundle domain; TIGRFAM: pyrimidine-nucleos [...]
    
 0.905
pyrR
Uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
     
 0.900
Isop_0435
COGs: COG0515 Serine/threonine protein kinase; InterProIPR000253: IPR017442: IPR020635: IPR002290: IPR 017441: IPR008271: IPR000719; KEGG: sro:Sros_3456 serine/threonine protein kinase-like protein; PFAM: Serine/threonine-protein kinase-like domain; Forkhead-associated protein; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, catalytic domain; Forkhead-associated protein; SPTR: Serine/threonine protein kinase-like protein; PFAM: Protein kinase domain; FHA domain.
       0.420
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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