STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Isop_0458Aminotransferase class IV; COGs: COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; InterPro IPR001544; KEGG: tkm:TK90_1969 D-amino-acid transaminase; PFAM: aminotransferase class IV; SPTR: D-amino-acid transaminase; PFAM: Aminotransferase class IV; TIGRFAM: D-amino acid aminotransferase. (330 aa)    
Predicted Functional Partners:
Isop_0123
COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR016160: IPR002872: IPR015590; KEGG: psl:Psta_0870 delta-1-pyrroline-5-carboxylate dehydrogenase; PFAM: Aldehyde Dehydrogenase; Proline dehydrogenase; SPTR: 1-pyrroline-5 carboxylate dehydrogenase; PFAM: Proline dehydrogenase; Aldehyde dehydrogenase family; TIGRFAM: delta-1-pyrroline-5-carboxylate dehydrogenase, group 2, putative; Belongs to the aldehyde dehydrogenase family.
   
 0.920
hisC
COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR005861: IPR004839: IPR004838; KEGG: psl:Psta_4386 histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; SPTR: Histidinol-phosphate aminotransferase; TIGRFAM: histidinol-phosphate aminotransferase; PFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
   
 
 0.915
Isop_0587
L-aspartate aminotransferase apoenzyme; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839: IPR004838: IPR001176; KEGG: plm:Plim_0135 aminotransferase class I and II; PFAM: aminotransferase class I and II; SPTR: Aspartate aminotransferase; PFAM: Aminotransferase class I and II.
    
 0.903
Isop_0457
Hypothetical protein; KEGG: dpe:Dper_GL18878 GL18878 gene product from transcript GL18878-RA; SPTR: GA17967.
       0.773
Isop_1175
KEGG: tra:Trad_0396 hypothetical protein; SPTR: Putative uncharacterized protein.
     0.695
Isop_0095
2-isopropylmalate synthase; COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterPro IPR000891: IPR005675: IPR002034: IPR013709; KEGG: plm:Plim_2070 2-isopropylmalate synthase/homocitrate synthase family protein; PFAM: pyruvate carboxyltransferase; LeuA allosteric (dimerisation) domain-containing protein; SPTR: 2-isopropylmalate synthase; TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; PFAM: LeuA allosteric (dimerisation) domain; HMGL-like; TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; Belongs to the alpha-IPM synthase [...]
  
 
 0.569
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
  
 
 0.569
ilvD
COGs: COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; InterPro IPR020558: IPR004404: IPR000581; KEGG: rxy:Rxyl_1326 dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; PRIAM: Dihydroxy-acid dehydratase; SPTR: Dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: Dehydratase family; TIGRFAM: dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
  
 
 0.539
Isop_3339
Dehydratase, YjhG/YagF family; COGs: COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; InterPro IPR017798: IPR000581: IPR020558; KEGG: psl:Psta_2493 dehydratase, YjhG/YagF family; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; PRIAM: Dihydroxy-acid dehydratase; SPTR: Dehydratase, YjhG/YagF family; TIGRFAM: dehydratase, YjhG/YagF family; PFAM: Dehydratase family; TIGRFAM: probable dehydratase, YjhG/YagF family; Belongs to the IlvD/Edd family.
  
 
 0.539
Isop_0713
Chorismate mutase; COGs: COG0077 Prephenate dehydratase; InterProIPR020822: IPR001086: IPR002912: IPR010957: IPR 002701: IPR008242; KEGG: plm:Plim_2048 prephenate dehydratase; PFAM: prephenate dehydratase; Chorismate mutase, type II; amino acid-binding ACT domain protein; SPTR: Prephenate dehydratase; TIGRFAM: chorismate mutase; PFAM: Prephenate dehydratase; Chorismate mutase type II; TIGRFAM: chorismate mutase domain of proteobacterial P-protein, clade 2.
     
 0.454
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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