STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_0462Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683: IPR006311; KEGG: plm:Plim_1207 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; SPTR: Probable dehydrogenase; PFAM: Oxidoreductase family, NAD-binding Rossmann fold. (438 aa)    
Predicted Functional Partners:
Isop_3665
Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR017909: IPR000683: IPR006311; KEGG: dfe:Dfer_4144 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; SPTR: Probable NADH-dependent dehydrogenase; PFAM: Oxidoreductase family, NAD-binding Rossmann fold.
  
     0.771
Isop_3656
Protein of unknown function DUF1080; InterPro IPR010496; KEGG: psl:Psta_2956 membrane-bound dehydrogenase domain protein; PFAM: protein of unknown function DUF1080; SPTR: Putative uncharacterized protein; PFAM: Domain of Unknown Function (DUF1080).
  
     0.768
Isop_3678
InterPro IPR010496; KEGG: dfe:Dfer_0069 protein of unknown function DUF1080; PFAM: protein of unknown function DUF1080; SPTR: Putative uncharacterized protein; PFAM: Domain of Unknown Function (DUF1080).
  
     0.753
Isop_3701
Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR017909: IPR000683: IPR006311; KEGG: plm:Plim_2857 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence.
  
     0.751
Isop_2611
InterPro IPR017969: IPR010496; KEGG: psl:Psta_2463 protein of unknown function DUF1080; PFAM: protein of unknown function DUF1080; SPTR: Putative uncharacterized protein; PFAM: Domain of Unknown Function (DUF1080).
  
     0.749
Isop_3354
Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR006311: IPR017909: IPR000683; KEGG: sli:Slin_6215 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; SPTR: Probable NADH-dependent dehydrogenase; PFAM: Oxidoreductase family, C-terminal alpha/beta domain; Oxidoreductase family, NAD-binding Rossmann fold.
  
     0.747
Isop_1220
Protein of unknown function DUF1080; InterPro IPR010496; KEGG: rba:RB9196 secreted glycosyl hydrolase; PFAM: protein of unknown function DUF1080; SPTR: Probable secreted glycosyl hydrolase; PFAM: Domain of Unknown Function (DUF1080).
  
     0.745
Isop_1244
Xylose isomerase domain-containing protein TIM barrel; COGs: COG3622 Hydroxypyruvate isomerase; InterPro IPR006311: IPR012307; KEGG: zpr:ZPR_4222 probable glyoxylate-induced protein; PFAM: Xylose isomerase domain-containing protein TIM barrel; SPTR: Probable glyoxylate-induced protein; PFAM: Xylose isomerase-like TIM barrel; Belongs to the hyi family.
 
    0.744
Isop_1476
Protein of unknown function DUF1080; InterPro IPR010496; KEGG: rba:RB569 hypothetical protein; PFAM: protein of unknown function DUF1080; SPTR: Putative uncharacterized protein; PFAM: Domain of Unknown Function (DUF1080).
  
     0.742
Isop_2526
Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR017909: IPR000683: IPR006311; KEGG: plm:Plim_3510 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase family, NAD-binding Rossmann fold.
  
     0.742
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.