STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Isop_0484Peptidase M1 membrane alanine aminopeptidase; COGs: COG0308 Aminopeptidase N; InterPro IPR014782: IPR015211; KEGG: amc:MADE_03140 putative cold-active aminopeptidase; secreted using a signal peptide; PFAM: Peptidase M1 membrane alanine aminopeptidase; Leukotriene A4 hydrolase; SPTR: Peptidase M1 membrane alanine aminopeptidase; PFAM: Leukotriene A4 hydrolase, C-terminal; Peptidase family M1. (671 aa)    
Predicted Functional Partners:
Isop_0485
Hypothetical protein; KEGG: sus:Acid_1892 isochorismatase hydrolase; SPTR: Isochorismatase hydrolase; PFAM: Isochorismatase family; Trehalose utilisation.
  
    0.775
Isop_0088
Peptidase S9B dipeptidylpeptidase IV domain protein; COGs: COG1506 Dipeptidyl aminopeptidase/acylaminoacyl-peptidase; InterPro IPR002469; KEGG: hoh:Hoch_4258 peptidase S9B dipeptidylpeptidase IV domain protein; PFAM: peptidase S9B dipeptidylpeptidase IV domain protein; SPTR: Peptidase S9B dipeptidylpeptidase IV domain protein; PFAM: Prolyl oligopeptidase family; Dipeptidyl peptidase IV (DPP IV) N-terminal region.
  
     0.692
miaA
tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.
 
      0.642
Isop_0486
VWFA-related domain protein; InterPro IPR002035: IPR017802; KEGG: plm:Plim_0632 hypothetical protein; PFAM: von Willebrand factor type A; SMART: von Willebrand factor type A; SPTR: Putative uncharacterized protein; TIGRFAM: VWFA-related Acidobacterial domain protein; PFAM: von Willebrand factor type A domain; TIGRFAM: VWFA-related Acidobacterial domain.
       0.547
Isop_0487
Forkhead-associated protein; InterPro IPR000253; KEGG: pic:PICST_67887 hypothetical protein; PFAM: Forkhead-associated protein; SPTR: Predicted protein; PFAM: FHA domain.
       0.547
Isop_1654
Peptidase S9B dipeptidylpeptidase IV domain protein; COGs: COG1506 Dipeptidyl aminopeptidase/acylaminoacyl-peptidase; InterPro IPR000834: IPR002469; KEGG: sus:Acid_5302 peptidase S9B dipeptidylpeptidase IV subunit; PFAM: peptidase S9B dipeptidylpeptidase IV domain protein; peptidase M14 carboxypeptidase A; SMART: peptidase M14 carboxypeptidase A; SPTR: Peptidase S9B, dipeptidylpeptidase IV domain protein; PFAM: Prolyl oligopeptidase family; Dipeptidyl peptidase IV (DPP IV) N-terminal region; Zinc carboxypeptidase.
  
     0.528
Isop_3003
Peptidase M16 domain protein; COGs: COG0612 Zn-dependent peptidase; InterPro IPR001431: IPR011765: IPR007863; KEGG: rmr:Rmar_0089 peptidase M16 domain protein; PFAM: peptidase M16 domain protein; SPTR: Peptidase M16 domain protein; PFAM: Peptidase M16 inactive domain; Insulinase (Peptidase family M16); Belongs to the peptidase M16 family.
  
 
   0.518
Isop_1883
Peptidase M28; COGs: COG2234 aminopeptidase; InterPro IPR007484; KEGG: rbi:RB2501_14084 probable aminopeptidase; PFAM: peptidase M28; SPTR: Peptidase M28; PFAM: Peptidase family M28.
  
 
 
 0.501
Isop_0483
COGs: COG0783 DNA-binding ferritin-like protein (oxidative damage protectant); InterPro IPR008331: IPR002177; KEGG: psl:Psta_1613 ferritin Dps family protein; PFAM: Ferritin Dps family protein; SPTR: Ferritin Dps family protein; PFAM: Ferritin-like domain; Belongs to the Dps family.
       0.485
Isop_1937
Abortive infection protein; COGs: COG1668 ABC-type Na+ efflux pump permease component; InterPro IPR003675; KEGG: psl:Psta_2528 abortive infection protein; PFAM: Abortive infection protein; SPTR: Probable sodium extrusion protein NatB; PFAM: CAAX amino terminal protease family.
 
     0.472
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
Server load: low (34%) [HD]