STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_0487Forkhead-associated protein; InterPro IPR000253; KEGG: pic:PICST_67887 hypothetical protein; PFAM: Forkhead-associated protein; SPTR: Predicted protein; PFAM: FHA domain. (564 aa)    
Predicted Functional Partners:
Isop_0486
VWFA-related domain protein; InterPro IPR002035: IPR017802; KEGG: plm:Plim_0632 hypothetical protein; PFAM: von Willebrand factor type A; SMART: von Willebrand factor type A; SPTR: Putative uncharacterized protein; TIGRFAM: VWFA-related Acidobacterial domain protein; PFAM: von Willebrand factor type A domain; TIGRFAM: VWFA-related Acidobacterial domain.
       0.780
Isop_0484
Peptidase M1 membrane alanine aminopeptidase; COGs: COG0308 Aminopeptidase N; InterPro IPR014782: IPR015211; KEGG: amc:MADE_03140 putative cold-active aminopeptidase; secreted using a signal peptide; PFAM: Peptidase M1 membrane alanine aminopeptidase; Leukotriene A4 hydrolase; SPTR: Peptidase M1 membrane alanine aminopeptidase; PFAM: Leukotriene A4 hydrolase, C-terminal; Peptidase family M1.
       0.547
Isop_0485
Hypothetical protein; KEGG: sus:Acid_1892 isochorismatase hydrolase; SPTR: Isochorismatase hydrolase; PFAM: Isochorismatase family; Trehalose utilisation.
       0.547
Isop_0044
COGs: COG0567 2-oxoglutarate dehydrogenase complex dehydrogenase (E1); InterPro IPR011603: IPR001017: IPR005475; KEGG: sfu:Sfum_3547 2-oxoglutarate dehydrogenase E1 component; PFAM: Transketolase central region; dehydrogenase E1 component; PRIAM: Oxoglutarate dehydrogenase (succinyl-transferring); SPTR: 2-oxoglutarate dehydrogenase, E1 component; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: Dehydrogenase E1 component; Transketolase, pyrimidine binding domain; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 component.
    
 
 0.537
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
Server load: low (20%) [HD]