STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_0494Protein of unknown function DUF820; InterPro IPR008538; KEGG: rca:Rcas_2194 hypothetical protein; PFAM: protein of unknown function DUF820; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF820). (320 aa)    
Predicted Functional Partners:
Isop_2029
Protein of unknown function DUF820; InterPro IPR008538; KEGG: rrs:RoseRS_2740 hypothetical protein; PFAM: protein of unknown function DUF820; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF820).
  
     0.645
Isop_2392
Protein of unknown function DUF790; COGs: COG3372 conserved hypothetical protein; InterPro IPR008508; KEGG: scl:sce6812 hypothetical protein; PFAM: protein of unknown function DUF790; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF790).
  
     0.575
Isop_2294
Modification methylase NspV; InterPro IPR002052: IPR002296; KEGG: rca:Rcas_1074 modification methylase NspV; SPTR: Modification methylase NspV.
 
     0.567
Isop_3372
KEGG: mar:MAE_40430 hypothetical protein; SPTR: Genome sequencing data, contig C279; PFAM: Protein of unknown function DUF82.
  
     0.564
rpsL
SSU ribosomal protein S12P; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
  
 
 0.540
Isop_3345
InterPro IPR004155; KEGG: rrs:RoseRS_1736 heat repeat-containing PBS lyase; PFAM: PBS lyase HEAT domain protein repeat-containing protein; SPTR: PBS lyase HEAT domain protein repeat-containing protein.
  
     0.538
Isop_1922
COGs: COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains; InterProIPR020046: IPR020047: IPR001098: IPR002421: IPR 008918: IPR002298: IPR018320: IPR019760; KEGG: plm:Plim_3011 DNA polymerase I; PFAM: DNA-directed DNA polymerase; 5'-3' exonuclease, N-terminal resolvase-like domain; 5'-3' exonuclease, SAM-fold domain; SMART: DNA-directed DNA polymerase; 5'-3' exonuclease; Helix-hairpin-helix domain protein class 2; SPTR: DNA polymerase I; TIGRFAM: DNA polymerase I; PFAM: 5'-3' exonuclease, C-terminal SAM fold; 5'-3' exonuclease, N-terminal resolvase-like domain; DNA polym [...]
     
 0.479
Isop_2219
Phycocyanin; InterPro IPR012128; KEGG: cyb:CYB_0575 phycobilisome protein; PFAM: Phycocyanin; SPTR: Phycobilisome protein; PFAM: Phycobilisome protein.
  
     0.478
Isop_1541
WD40 repeat, subgroup; COGs: COG2319 FOG: WD40 repeat; InterProIPR019782: IPR017986: IPR019775: IPR001680: IPR 019781; KEGG: rrs:RoseRS_0892 WD-40 repeat-containing protein; PFAM: WD40 repeat, subgroup; SMART: WD-40 repeat-containing protein; SPTR: WD-40 repeat; PFAM: WD domain, G-beta repeat.
  
    0.459
Isop_2214
Glutamate synthase (NADH) large subunit; COGs: COG0069 Glutamate synthase domain 2; InterProIPR000583: IPR006982: IPR002932: IPR002489: IPR 017932; KEGG: ttr:Tter_0474 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: Glutamate synthase (Ferredoxin); PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
     
 0.454
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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