| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Isop_0512 | Isop_0513 | Isop_0512 | Isop_0513 | CRISPR-associated protein, GSU0054; InterPro IPR019089; KEGG: hoh:Hoch_4849 hypothetical protein; PFAM: CRISPR-associated protein, GSU0054; SPTR: Putative uncharacterized protein; manually curated; PFAM: CRISPR-associated protein, GSU0054 family (Cas_GSU0054). | Penicillinase repressor; InterPro IPR005650; KEGG: hoh:Hoch_4716 transcriptional repressor, CopY family; PFAM: Penicillinase repressor; SPTR: Transcriptional repressor, CopY family protein; PFAM: Penicillinase repressor. | 0.564 |
| Isop_0512 | cas2 | Isop_0512 | Isop_0511 | CRISPR-associated protein, GSU0054; InterPro IPR019089; KEGG: hoh:Hoch_4849 hypothetical protein; PFAM: CRISPR-associated protein, GSU0054; SPTR: Putative uncharacterized protein; manually curated; PFAM: CRISPR-associated protein, GSU0054 family (Cas_GSU0054). | CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. | 0.873 |
| Isop_0513 | Isop_0512 | Isop_0513 | Isop_0512 | Penicillinase repressor; InterPro IPR005650; KEGG: hoh:Hoch_4716 transcriptional repressor, CopY family; PFAM: Penicillinase repressor; SPTR: Transcriptional repressor, CopY family protein; PFAM: Penicillinase repressor. | CRISPR-associated protein, GSU0054; InterPro IPR019089; KEGG: hoh:Hoch_4849 hypothetical protein; PFAM: CRISPR-associated protein, GSU0054; SPTR: Putative uncharacterized protein; manually curated; PFAM: CRISPR-associated protein, GSU0054 family (Cas_GSU0054). | 0.564 |
| Isop_0513 | Isop_0945 | Isop_0513 | Isop_0945 | Penicillinase repressor; InterPro IPR005650; KEGG: hoh:Hoch_4716 transcriptional repressor, CopY family; PFAM: Penicillinase repressor; SPTR: Transcriptional repressor, CopY family protein; PFAM: Penicillinase repressor. | FG-GAP repeat protein; InterPro IPR013517; KEGG: plm:Plim_3628 FG-GAP repeat protein; PFAM: FG-GAP repeat protein; SPTR: Lipoprotein, putative. | 0.408 |
| Isop_0513 | Isop_1191 | Isop_0513 | Isop_1191 | Penicillinase repressor; InterPro IPR005650; KEGG: hoh:Hoch_4716 transcriptional repressor, CopY family; PFAM: Penicillinase repressor; SPTR: Transcriptional repressor, CopY family protein; PFAM: Penicillinase repressor. | ASPIC/UnbV domain protein; InterPro IPR013517: IPR011519; KEGG: sus:Acid_1964 ASPIC/UnbV domain-containing protein; PFAM: ASPIC/UnbV domain protein; FG-GAP repeat protein; SPTR: ASPIC/UnbV domain protein; PFAM: ASPIC and UnbV. | 0.468 |
| Isop_0513 | Isop_1967 | Isop_0513 | Isop_1967 | Penicillinase repressor; InterPro IPR005650; KEGG: hoh:Hoch_4716 transcriptional repressor, CopY family; PFAM: Penicillinase repressor; SPTR: Transcriptional repressor, CopY family protein; PFAM: Penicillinase repressor. | ASPIC/UnbV domain protein; InterPro IPR013517: IPR011519; KEGG: sus:Acid_0215 ASPIC/UnbV domain-containing protein; PFAM: ASPIC/UnbV domain protein; FG-GAP repeat protein; SPTR: ASPIC/UnbV domain protein; PFAM: ASPIC and UnbV; FG-GAP repeat. | 0.523 |
| Isop_0513 | Isop_2777 | Isop_0513 | Isop_2777 | Penicillinase repressor; InterPro IPR005650; KEGG: hoh:Hoch_4716 transcriptional repressor, CopY family; PFAM: Penicillinase repressor; SPTR: Transcriptional repressor, CopY family protein; PFAM: Penicillinase repressor. | ASPIC/UnbV domain protein; InterPro IPR013517: IPR011519; KEGG: aba:Acid345_0425 hypothetical protein; PFAM: ASPIC/UnbV domain protein; FG-GAP repeat protein; SPTR: Putative uncharacterized protein; PFAM: ASPIC and UnbV; FG-GAP repeat. | 0.489 |
| Isop_0513 | Isop_3064 | Isop_0513 | Isop_3064 | Penicillinase repressor; InterPro IPR005650; KEGG: hoh:Hoch_4716 transcriptional repressor, CopY family; PFAM: Penicillinase repressor; SPTR: Transcriptional repressor, CopY family protein; PFAM: Penicillinase repressor. | ASPIC/UnbV domain protein; InterPro IPR013517: IPR011519; KEGG: rba:RB11088 hypothetical protein; PFAM: ASPIC/UnbV domain protein; FG-GAP repeat protein; SPTR: Similar to ASPIC; PFAM: ASPIC and UnbV; FG-GAP repeat. | 0.539 |
| Isop_0513 | Isop_3151 | Isop_0513 | Isop_3151 | Penicillinase repressor; InterPro IPR005650; KEGG: hoh:Hoch_4716 transcriptional repressor, CopY family; PFAM: Penicillinase repressor; SPTR: Transcriptional repressor, CopY family protein; PFAM: Penicillinase repressor. | Peptidase M56 BlaR1; InterPro IPR008756; KEGG: sus:Acid_5553 peptidase M56, BlaR1; PFAM: peptidase M56 BlaR1; SPTR: Peptidase M56, BlaR1. | 0.563 |
| Isop_0513 | Isop_3356 | Isop_0513 | Isop_3356 | Penicillinase repressor; InterPro IPR005650; KEGG: hoh:Hoch_4716 transcriptional repressor, CopY family; PFAM: Penicillinase repressor; SPTR: Transcriptional repressor, CopY family protein; PFAM: Penicillinase repressor. | ASPIC/UnbV domain protein; InterPro IPR019734: IPR013026: IPR011519; KEGG: ote:Oter_2945 TPR repeat-containing protein; PFAM: ASPIC/UnbV domain protein; SPTR: TPR repeat-containing protein; PFAM: ASPIC and UnbV. | 0.508 |
| Isop_0513 | cas2 | Isop_0513 | Isop_0511 | Penicillinase repressor; InterPro IPR005650; KEGG: hoh:Hoch_4716 transcriptional repressor, CopY family; PFAM: Penicillinase repressor; SPTR: Transcriptional repressor, CopY family protein; PFAM: Penicillinase repressor. | CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. | 0.428 |
| Isop_0945 | Isop_0513 | Isop_0945 | Isop_0513 | FG-GAP repeat protein; InterPro IPR013517; KEGG: plm:Plim_3628 FG-GAP repeat protein; PFAM: FG-GAP repeat protein; SPTR: Lipoprotein, putative. | Penicillinase repressor; InterPro IPR005650; KEGG: hoh:Hoch_4716 transcriptional repressor, CopY family; PFAM: Penicillinase repressor; SPTR: Transcriptional repressor, CopY family protein; PFAM: Penicillinase repressor. | 0.408 |
| Isop_0945 | Isop_2777 | Isop_0945 | Isop_2777 | FG-GAP repeat protein; InterPro IPR013517; KEGG: plm:Plim_3628 FG-GAP repeat protein; PFAM: FG-GAP repeat protein; SPTR: Lipoprotein, putative. | ASPIC/UnbV domain protein; InterPro IPR013517: IPR011519; KEGG: aba:Acid345_0425 hypothetical protein; PFAM: ASPIC/UnbV domain protein; FG-GAP repeat protein; SPTR: Putative uncharacterized protein; PFAM: ASPIC and UnbV; FG-GAP repeat. | 0.411 |
| Isop_0945 | Isop_3151 | Isop_0945 | Isop_3151 | FG-GAP repeat protein; InterPro IPR013517; KEGG: plm:Plim_3628 FG-GAP repeat protein; PFAM: FG-GAP repeat protein; SPTR: Lipoprotein, putative. | Peptidase M56 BlaR1; InterPro IPR008756; KEGG: sus:Acid_5553 peptidase M56, BlaR1; PFAM: peptidase M56 BlaR1; SPTR: Peptidase M56, BlaR1. | 0.634 |
| Isop_0945 | Isop_3356 | Isop_0945 | Isop_3356 | FG-GAP repeat protein; InterPro IPR013517; KEGG: plm:Plim_3628 FG-GAP repeat protein; PFAM: FG-GAP repeat protein; SPTR: Lipoprotein, putative. | ASPIC/UnbV domain protein; InterPro IPR019734: IPR013026: IPR011519; KEGG: ote:Oter_2945 TPR repeat-containing protein; PFAM: ASPIC/UnbV domain protein; SPTR: TPR repeat-containing protein; PFAM: ASPIC and UnbV. | 0.534 |
| Isop_1191 | Isop_0513 | Isop_1191 | Isop_0513 | ASPIC/UnbV domain protein; InterPro IPR013517: IPR011519; KEGG: sus:Acid_1964 ASPIC/UnbV domain-containing protein; PFAM: ASPIC/UnbV domain protein; FG-GAP repeat protein; SPTR: ASPIC/UnbV domain protein; PFAM: ASPIC and UnbV. | Penicillinase repressor; InterPro IPR005650; KEGG: hoh:Hoch_4716 transcriptional repressor, CopY family; PFAM: Penicillinase repressor; SPTR: Transcriptional repressor, CopY family protein; PFAM: Penicillinase repressor. | 0.468 |
| Isop_1967 | Isop_0513 | Isop_1967 | Isop_0513 | ASPIC/UnbV domain protein; InterPro IPR013517: IPR011519; KEGG: sus:Acid_0215 ASPIC/UnbV domain-containing protein; PFAM: ASPIC/UnbV domain protein; FG-GAP repeat protein; SPTR: ASPIC/UnbV domain protein; PFAM: ASPIC and UnbV; FG-GAP repeat. | Penicillinase repressor; InterPro IPR005650; KEGG: hoh:Hoch_4716 transcriptional repressor, CopY family; PFAM: Penicillinase repressor; SPTR: Transcriptional repressor, CopY family protein; PFAM: Penicillinase repressor. | 0.523 |
| Isop_2777 | Isop_0513 | Isop_2777 | Isop_0513 | ASPIC/UnbV domain protein; InterPro IPR013517: IPR011519; KEGG: aba:Acid345_0425 hypothetical protein; PFAM: ASPIC/UnbV domain protein; FG-GAP repeat protein; SPTR: Putative uncharacterized protein; PFAM: ASPIC and UnbV; FG-GAP repeat. | Penicillinase repressor; InterPro IPR005650; KEGG: hoh:Hoch_4716 transcriptional repressor, CopY family; PFAM: Penicillinase repressor; SPTR: Transcriptional repressor, CopY family protein; PFAM: Penicillinase repressor. | 0.489 |
| Isop_2777 | Isop_0945 | Isop_2777 | Isop_0945 | ASPIC/UnbV domain protein; InterPro IPR013517: IPR011519; KEGG: aba:Acid345_0425 hypothetical protein; PFAM: ASPIC/UnbV domain protein; FG-GAP repeat protein; SPTR: Putative uncharacterized protein; PFAM: ASPIC and UnbV; FG-GAP repeat. | FG-GAP repeat protein; InterPro IPR013517; KEGG: plm:Plim_3628 FG-GAP repeat protein; PFAM: FG-GAP repeat protein; SPTR: Lipoprotein, putative. | 0.411 |
| Isop_3064 | Isop_0513 | Isop_3064 | Isop_0513 | ASPIC/UnbV domain protein; InterPro IPR013517: IPR011519; KEGG: rba:RB11088 hypothetical protein; PFAM: ASPIC/UnbV domain protein; FG-GAP repeat protein; SPTR: Similar to ASPIC; PFAM: ASPIC and UnbV; FG-GAP repeat. | Penicillinase repressor; InterPro IPR005650; KEGG: hoh:Hoch_4716 transcriptional repressor, CopY family; PFAM: Penicillinase repressor; SPTR: Transcriptional repressor, CopY family protein; PFAM: Penicillinase repressor. | 0.539 |