Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Isop_0537Repeat-companion domain protein; InterPro IPR003590: IPR014338; KEGG: hau:Haur_4051 hypothetical protein; SPTR: Leucine-rich repeat-containing protein typical subtype; TIGRFAM: repeat-companion domain protein; TIGRFAM: repeat-companion domain TIGR02996. (316 aa)    
Predicted Functional Partners:
Isop_0540
ATPase associated with various cellular activities AAA_5; COGs: COG0714 MoxR-like ATPase; InterPro IPR011704: IPR003593; KEGG: mxa:MXAN_2895 AAA family ATPase; PFAM: ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; SPTR: ATPase, AAA family; PFAM: AAA domain (dynein-related subfamily).
 
     0.783
Isop_0390
Hypothetical protein; InterPro IPR003590; KEGG: hau:Haur_4051 hypothetical protein; SPTR: Leucine-rich repeat-containing protein typical subtype; TIGRFAM: repeat-companion domain TIGR02996.
  
     0.773
Isop_0538
Hypothetical protein; KEGG: cfa:478778 xin actin-binding repeat containing 2; SPTR: Putative uncharacterized protein Xirp2.
       0.773
Isop_1833
CRISPR-associated protein, GSU0054; InterPro IPR019089; KEGG: hoh:Hoch_4849 hypothetical protein; PFAM: CRISPR-associated protein, GSU0054; SPTR: Putative uncharacterized protein; PFAM: CRISPR-associated protein, GSU0054 family (Cas_GSU0054); TIGRFAM: CRISPR-associated protein, GSU0054 family.
  
     0.754
Isop_2646
Dual specificity protein phosphatase; InterPro IPR000387: IPR000340; KEGG: olu:OSTLU_7942 predicted protein; PFAM: Dual specificity protein phosphatase; SPTR: Predicted protein; PFAM: Dual specificity phosphatase, catalytic domain.
  
     0.753
Isop_3202
Hypothetical protein; KEGG: ttu:TERTU_3103 putative type I phosphodiesterase/nucleotide pyrophosphatase; SPTR: Putative type I phosphodiesterase/nucleotide pyrophosphatase; PFAM: Type I phosphodiesterase / nucleotide pyrophosphatase.
  
     0.745
Isop_1834
CRISPR-associated protein, Csx4 family; InterPro IPR013403; KEGG: hoh:Hoch_4848 CRISPR-associated protein GSU0053; PFAM: CRISPR-associated protein GSU0053; SPTR: CRISPR-associated protein GSU0053; PFAM: CRISPR-associated protein GSU0053 (Cas_GSU0053); TIGRFAM: CRISPR-associated protein, GSU0053 family, N-terminal domain.
  
     0.734
Isop_1832
COGs: COG1203 helicase; InterPro IPR013444: IPR006483; KEGG: hoh:Hoch_4850 CRISPR-associated helicase Cas3, Anaes-subtype; SPTR: CRISPR-associated helicase Cas3, Anaes-subtype; TIGRFAM: CRISPR-associated helicase Cas3, Anaes-subtype; CRISPR-associated HD domain protein; TIGRFAM: CRISPR-associated endonuclease Cas3-HD; CRISPR-associated helicase Cas3, Anaes-subtype.
  
     0.722
Isop_3082
WD40 repeat, subgroup; COGs: COG2319 FOG: WD40 repeat; InterPro IPR001680: IPR019782: IPR017986: IPR019781; KEGG: hoh:Hoch_3099 serine/threonine protein kinase with WD40 repeats; PFAM: WD40 repeat, subgroup; SMART: WD-40 repeat-containing protein; SPTR: Serine/threonine protein kinase with WD40 repeats; PFAM: WD domain, G-beta repeat.
  
     0.717
Isop_2419
YD repeat protein; COGs: COG3209 Rhs family protein; InterPro IPR003587: IPR006530: IPR006141; KEGG: plm:Plim_1036 AmoP; PFAM: YD repeat-containing protein; SMART: Hedgehog/intein hint domain protein; SPTR: AmoP; TIGRFAM: YD repeat protein; PFAM: RHS Repeat; Protein of unknown function (DUF1557); TIGRFAM: RHS repeat-associated core domain; YD repeat (two copies).
  
     0.716
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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