Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Isop_0625Hypothetical protein; KEGG: drt:Dret_1844 methyltransferase type 11; SPTR: Methyltransferase type 11. (101 aa)    
Predicted Functional Partners:
Isop_0626
Efflux transporter, RND family, MFP subunit; COGs: COG1566 Multidrug resistance efflux pump; InterPro IPR006143; KEGG: scl:sce2804 RND family efflux transporter MFP subunit; PFAM: secretion protein HlyD family protein; SPTR: Putative HlyD-like secretion protein; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: HlyD family secretion protein; TIGRFAM: RND family efflux transporter, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
       0.773
Isop_0627
Acriflavin resistance protein; COGs: COG0841 Cation/multidrug efflux pump; InterPro IPR001036; KEGG: scl:sce2805 hypothetical protein; PFAM: acriflavin resistance protein; SPTR: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family protein; PFAM: AcrB/AcrD/AcrF family; TIGRFAM: The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
       0.412
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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