STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Isop_0640NMT1/THI5 like domain protein; COGs: COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic components; KEGG: plm:Plim_2868 NMT1/THI5 like domain protein; SPTR: NMT1/THI5 like domain protein; PFAM: NMT1/THI5 like. (386 aa)    
Predicted Functional Partners:
Isop_0639
Binding-protein-dependent transport systems inner membrane component; COGs: COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system permease component; InterPro IPR000515; KEGG: plm:Plim_2867 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component.
 
 
 0.993
Isop_0638
ABC transporter related protein; COGs: COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system ATPase component; InterPro IPR003439: IPR003593: IPR017871; KEGG: plm:Plim_2866 ABC transporter related protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related protein; PFAM: ABC transporter.
 
 
 0.977
Isop_0703
COGs: COG0347 Nitrogen regulatory protein PII; InterPro IPR002187; KEGG: psl:Psta_4489 nitrogen regulatory protein P-II; PFAM: nitrogen regulatory protein P-II; SPTR: Nitrogen regulatory protein P-II; PFAM: Nitrogen regulatory protein P-II.
   
 
 0.641
Isop_1563
COGs: COG0347 Nitrogen regulatory protein PII; InterPro IPR002187; KEGG: reu:Reut_A0291 nitrogen regulatory protein P-II; PFAM: nitrogen regulatory protein P-II; SPTR: Nitrogen regulatory protein P-II; PFAM: Nitrogen regulatory protein P-II.
   
 
 0.641
Isop_2513
NADPH-dependent FMN reductase; COGs: COG0431 flavoprotein; InterPro IPR005025; KEGG: wch:wcw_1265 NADPH-dependent FMN reductase; PFAM: NADPH-dependent FMN reductase; SPTR: Putative uncharacterized protein; PFAM: NADPH-dependent FMN reductase.
 
  
 0.579
cysC
Sulfate adenylyltransferase; Catalyzes the synthesis of activated sulfate.
  
  
 0.502
Isop_0643
Peptidase A24A prepilin type IV; InterPro IPR000045; KEGG: plm:Plim_1841 peptidase A24A domain protein; PFAM: peptidase A24A prepilin type IV; SPTR: Probable type 4 prepilin-like proteins leader peptide processing enzyme; PFAM: Type IV leader peptidase family.
       0.467
aroE
Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA); Belongs to the type-I 3-dehydroquinase family.
       0.464
Isop_2214
Glutamate synthase (NADH) large subunit; COGs: COG0069 Glutamate synthase domain 2; InterProIPR000583: IPR006982: IPR002932: IPR002489: IPR 017932; KEGG: ttr:Tter_0474 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: Glutamate synthase (Ferredoxin); PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
   
  
 0.459
aroK
Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
       0.458
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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