STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_0649Heat shock protein Hsp20; COGs: COG0071 Molecular chaperone (small heat shock protein); InterPro IPR002068; KEGG: plm:Plim_1175 heat shock protein HSP20; PFAM: heat shock protein Hsp20; SPTR: Heat shock protein, HSP20 family; PFAM: Hsp20/alpha crystallin family; Belongs to the small heat shock protein (HSP20) family. (147 aa)    
Predicted Functional Partners:
Isop_0650
Heat shock protein Hsp20; COGs: COG0071 Molecular chaperone (small heat shock protein); InterPro IPR002068; KEGG: csa:Csal_3255 heat shock protein HSP20; PFAM: heat shock protein Hsp20; SPTR: Small heat shock protein (Class I); PFAM: Hsp20/alpha crystallin family; Belongs to the small heat shock protein (HSP20) family.
 
  
  0.988
Isop_2362
Heat shock protein Hsp20; COGs: COG0071 Molecular chaperone (small heat shock protein); InterPro IPR002068; KEGG: tye:THEYE_A1927 heat shock protein, HSP20 family; PFAM: heat shock protein Hsp20; SPTR: Heat shock protein, Hsp20 family; PFAM: Hsp20/alpha crystallin family.
  
  
 
0.925
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
  
 
 0.654
clpB
ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
  
 
 0.616
Isop_0962
ATPase AAA-2 domain protein; COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterProIPR003593: IPR001943: IPR004176: IPR003959: IPR 013093: IPR019489: IPR001270: IPR018368; KEGG: plm:Plim_0603 ATPase AAA-2 domain protein; PFAM: ATPase AAA-2 domain protein; Clp domain protein; AAA ATPase central domain protein; UvrB/UvrC protein; Clp ATPase-like; SMART: AAA ATPase; SPTR: ATPase AAA-2 domain protein; PFAM: AAA domain (Cdc48 subfamily); Clp amino terminal domain; C-terminal, D2-small domain, of ClpB protein; ATPase family associated with various cellular activities (AAA [...]
  
 
 0.616
Isop_0061
COGs: COG0174 Glutamine synthetase; InterPro IPR004809: IPR008147: IPR008146; KEGG: psl:Psta_1754 glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; SPTR: Glutamine synthetase; TIGRFAM: glutamine synthetase, type I; PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase, beta-Grasp domain; TIGRFAM: glutamine synthetase, type I.
    
 
 0.573
Isop_0648
Hypothetical protein; InterPro IPR001789; KEGG: rxy:Rxyl_2770 response regulator receiver protein; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain.
       0.468
Isop_1679
ABC transporter related protein; COGs: COG1117 ABC-type phosphate transport system ATPase component; InterProIPR000387: IPR003439: IPR017871: IPR016130: IPR 003593: IPR003595: IPR000340; KEGG: dac:Daci_1595 ABC transporter related; PFAM: ABC transporter related; Dual specificity protein phosphatase; SMART: AAA ATPase; Protein-tyrosine phosphatase, catalytic; SPTR: ABC transporter related; PFAM: ABC transporter; Dual specificity phosphatase, catalytic domain.
    
   0.446
Isop_0651
KEGG: plm:Plim_3756 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.426
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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