STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
argBN-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (315 aa)    
Predicted Functional Partners:
argC
N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
 
 0.998
argJ
Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.
 
 0.997
argD
COGs: COG4992 Ornithine/acetylornithine aminotransferase; InterPro IPR005814: IPR004636; KEGG: psl:Psta_2678 acetylornithine and succinylornithine aminotransferase; PFAM: aminotransferase class-III; SPTR: Acetylornithine and succinylornithine aminotransferase; TIGRFAM: acetylornithine and succinylornithine aminotransferase; PFAM: Aminotransferase class-III; TIGRFAM: acetylornithine and succinylornithine aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
 
  
 0.974
Isop_2738
GCN5-related N-acetyltransferase; COGs: COG1246 N-acetylglutamate synthase and related acetyltransferase; InterPro IPR000182; KEGG: dau:Daud_1142 acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: GCN5-related N-acetyltransferase; PFAM: Acetyltransferase (GNAT) family.
  
 
 0.936
argH
COGs: COG0165 Argininosuccinate lyase; InterPro IPR009049: IPR000362: IPR003031: IPR020557; KEGG: psl:Psta_0383 argininosuccinate lyase; PFAM: fumarate lyase; SPTR: Argininosuccinate lyase; TIGRFAM: argininosuccinate lyase; manually curated; PFAM: Lyase; TIGRFAM: argininosuccinate lyase.
 
  
 0.910
arcB
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
 
  
 0.908
Isop_2909
COGs: COG0137 Argininosuccinate synthase; InterPro IPR018223: IPR001518; KEGG: psl:Psta_3843 argininosuccinate synthase; PFAM: argininosuccinate synthase; PRIAM: Argininosuccinate synthase; SPTR: Argininosuccinate synthase; TIGRFAM: argininosuccinate synthase; PFAM: Arginosuccinate synthase; TIGRFAM: argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
 
  
 0.896
Isop_0703
COGs: COG0347 Nitrogen regulatory protein PII; InterPro IPR002187; KEGG: psl:Psta_4489 nitrogen regulatory protein P-II; PFAM: nitrogen regulatory protein P-II; SPTR: Nitrogen regulatory protein P-II; PFAM: Nitrogen regulatory protein P-II.
    
 
 0.785
Isop_1563
COGs: COG0347 Nitrogen regulatory protein PII; InterPro IPR002187; KEGG: reu:Reut_A0291 nitrogen regulatory protein P-II; PFAM: nitrogen regulatory protein P-II; SPTR: Nitrogen regulatory protein P-II; PFAM: Nitrogen regulatory protein P-II.
    
 
 0.785
carA
COGs: COG0505 Carbamoylphosphate synthase small subunit; InterProIPR006274: IPR017926: IPR002474: IPR000991: IPR 001317: IPR011702; KEGG: psl:Psta_4606 carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; SPTR: Carbamoyl-phosphate synthase, small chain; TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; Glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family.
  
  
 0.699
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.