STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_0682D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; COGs: COG1052 Lactate dehydrogenase and related dehydrogenase; InterPro IPR006139: IPR006140; KEGG: mta:Moth_1954 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; SPTR: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. (344 aa)    
Predicted Functional Partners:
Isop_0800
FAD linked oxidase domain protein; COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR006094: IPR004113: IPR016166; KEGG: psl:Psta_2648 FAD linked oxidase domain protein; PFAM: FAD linked oxidase domain protein; SPTR: Glycolate oxidase subunit; PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain.
   
 0.908
Isop_1441
COGs: COG1929 Glycerate kinase; InterPro IPR004381; KEGG: mta:Moth_0404 glycerate kinase; PFAM: glycerate kinase; PRIAM: Glycerate kinase; SPTR: Glycerate kinase; TIGRFAM: glycerate kinase; PFAM: Glycerate kinase family; TIGRFAM: glycerate kinase; Belongs to the glycerate kinase type-1 family.
    
 0.908
Isop_1867
FAD linked oxidase domain protein; COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR006094: IPR004113: IPR016166; KEGG: psl:Psta_2649 FAD linked oxidase domain protein; PFAM: FAD linked oxidase domain protein; SPTR: Glycolate oxidase subunit; PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain; TIGRFAM: glycolate oxidase, subunit GlcD.
   
 0.908
Isop_3726
Alanine-glyoxylate aminotransferase apoenzyme; COGs: COG0075 Serine-pyruvate aminotransferase/ aspartate aminotransferase; InterPro IPR020578: IPR000192; KEGG: psl:Psta_2949 aminotransferase class V; PFAM: aminotransferase class V; SPTR: Aminotransferase class V; PFAM: Aminotransferase class-V.
  
 
 0.908
Isop_0345
Putative transcriptional regulator, GntR family; COGs: COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; InterPro IPR004839; KEGG: caa:Caka_0677 putative transcriptional regulator, GntR family; PFAM: aminotransferase class I and II; SPTR: Aminotransferase; PFAM: Aminotransferase class I and II.
  
 
  0.904
Isop_3401
COGs: COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase; InterPro IPR000887; KEGG: psl:Psta_4168 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase; SPTR: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; TIGRFAM: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase; TIGRFAM: Entner-Doudoroff aldolase.
    
  0.903
Isop_0799
COGs: COG0247 Fe-S oxidoreductase; InterPro IPR004017: IPR017896: IPR017900; KEGG: psl:Psta_2647 protein of unknown function DUF224 cysteine-rich region domain protein; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: Putative uncharacterized protein; PFAM: Cysteine-rich domain.
    
  0.901
Isop_1244
Xylose isomerase domain-containing protein TIM barrel; COGs: COG3622 Hydroxypyruvate isomerase; InterPro IPR006311: IPR012307; KEGG: zpr:ZPR_4222 probable glyoxylate-induced protein; PFAM: Xylose isomerase domain-containing protein TIM barrel; SPTR: Probable glyoxylate-induced protein; PFAM: Xylose isomerase-like TIM barrel; Belongs to the hyi family.
   
 
  0.901
Isop_2183
COGs: COG3622 Hydroxypyruvate isomerase; InterPro IPR012307; KEGG: cag:Cagg_1301 xylose isomerase domain protein TIM barrel; PFAM: Xylose isomerase domain-containing protein TIM barrel; PRIAM: Hydroxypyruvate isomerase; SPTR: Xylose isomerase domain protein TIM barrel; PFAM: Xylose isomerase-like TIM barrel.
   
 
  0.901
Isop_0681
Glycoside hydrolase family 10; COGs: COG3693 Beta-1 4-xylanase; KEGG: plm:Plim_3847 glycoside hydrolase family 10; SPTR: Glycoside hydrolase family 10.
       0.773
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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