STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_0722Tetratricopeptide TPR_1 repeat-containing protein; InterPro IPR001440: IPR019734: IPR013026: IPR019794; KEGG: ade:Adeh_2705 response regulator receiver; PFAM: Tetratricopeptide TPR_1 repeat-containing protein; SPTR: Response regulator receiver. (1565 aa)    
Predicted Functional Partners:
Isop_3422
Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
   
   0.786
nhaA
Sodium/proton antiporter, NhaA family; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
   
    0.637
nhaA-2
Sodium/proton antiporter, NhaA family; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
   
    0.637
Isop_2393
Type III restriction protein res subunit; COGs: COG1061 DNA or RNA helicase of superfamily II; InterPro IPR014001: IPR001650: IPR006935: IPR014021; KEGG: scl:sce6811 DNA repair protein; PFAM: type III restriction protein res subunit; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: DNA repair protein; PFAM: Helicase conserved C-terminal domain; Type III restriction enzyme, res subunit.
 
 
   0.537
Isop_3619
Beta-lactamase; Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.
 
     0.537
Isop_3523
WD40 repeat, subgroup; COGs: COG2319 FOG: WD40 repeat; InterProIPR019782: IPR017986: IPR009056: IPR019781: IPR 019775: IPR001680; KEGG: psl:Psta_2093 planctomycete cytochrome c; PFAM: WD40 repeat, subgroup; SPTR: Planctomycete cytochrome C; PFAM: WD domain, G-beta repeat; Planctomycete cytochrome C.
 
 
 0.514
Isop_3082
WD40 repeat, subgroup; COGs: COG2319 FOG: WD40 repeat; InterPro IPR001680: IPR019782: IPR017986: IPR019781; KEGG: hoh:Hoch_3099 serine/threonine protein kinase with WD40 repeats; PFAM: WD40 repeat, subgroup; SMART: WD-40 repeat-containing protein; SPTR: Serine/threonine protein kinase with WD40 repeats; PFAM: WD domain, G-beta repeat.
 
 
  0.512
Isop_1753
Hypothetical protein; InterPro IPR019734: IPR013026; KEGG: cts:Ctha_0597 TPR repeat-containing protein; SPTR: TPR repeat-containing protein; PFAM: Tetratricopeptide repeat.
  
     0.488
Isop_2392
Protein of unknown function DUF790; COGs: COG3372 conserved hypothetical protein; InterPro IPR008508; KEGG: scl:sce6812 hypothetical protein; PFAM: protein of unknown function DUF790; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF790).
  
     0.476
Isop_3467
Hypothetical protein; KEGG: rba:RB6221 signal peptide; SPTR: Putative uncharacterized protein.
  
     0.475
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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