STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
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[Homology]
Score
Isop_0723COGs: COG1052 Lactate dehydrogenase and related dehydrogenase; InterPro IPR006139: IPR006140; KEGG: sfu:Sfum_3136 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; PRIAM: Phosphoglycerate dehydrogenase; SPTR: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. (336 aa)    
Predicted Functional Partners:
Isop_0186
COGs: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenase; InterPro IPR006236: IPR006140: IPR006139: IPR002912; KEGG: plm:Plim_2827 D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; amino acid-binding ACT domain protein; PRIAM: Phosphoglycerate dehydrogenase; SPTR: D-3-phosphoglycerate dehydrogenase; TIGRFAM: D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; ACT domain; D-isomer specific 2-hydroxyacid [...]
 
 
0.924
gpmA
Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
    
 0.904
Isop_0585
COGs: COG3635 phosphoglycerate mutase AP superfamily; InterPro IPR019304: IPR006124: IPR004456: IPR013371; KEGG: psl:Psta_4304 proposed homoserine kinase; PFAM: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; metalloenzyme domain protein; PRIAM: Phosphoglycerate mutase; SPTR: Cofactor-independent phosphoglycerate mutase; TIGRFAM: proposed homoserine kinase; phosphonopyruvate decarboxylase-related protein; PFAM: Metalloenzyme superfamily; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; TIGRFAM: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, archae [...]
   
 
  0.900
Isop_0724
DNA photolyase FAD-binding protein; COGs: COG0415 Deoxyribodipyrimidine photolyase; InterPro IPR006050: IPR005101; KEGG: aca:ACP_1875 deoxyribodipyrimidine photolyase; PFAM: DNA photolyase FAD-binding; DNA photolyase domain protein; SPTR: Deoxyribodipyrimidine photolyase; PFAM: FAD binding domain of DNA photolyase; DNA photolyase; TIGRFAM: photolyase PhrII.
       0.484
Isop_0725
Hypothetical protein; KEGG: rba:RB5663 signal peptide; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1570).
       0.484
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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