| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Isop_0131 | Isop_0734 | Isop_0131 | Isop_0734 | KpsF/GutQ family protein; COGs: COG0794 sugar phosphate isomerase involved in capsule formation; InterPro IPR000644: IPR004800: IPR018506: IPR001347; KEGG: psl:Psta_0845 KpsF/GutQ family protein; PFAM: sugar isomerase (SIS); CBS domain containing protein; PRIAM: Arabinose-5-phosphate isomerase; SPTR: KpsF/GutQ family protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain; SIS domain; TIGRFAM: KpsF/GutQ family protein. | ABC transporter related protein; COGs: COG1137 ABC-type (unclassified) transport system ATPase component; InterPro IPR003439: IPR003593: IPR017871; KEGG: psl:Psta_0620 ABC transporter related protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related protein; PFAM: ABC transporter. | 0.761 |
| Isop_0131 | Isop_0751 | Isop_0131 | Isop_0751 | KpsF/GutQ family protein; COGs: COG0794 sugar phosphate isomerase involved in capsule formation; InterPro IPR000644: IPR004800: IPR018506: IPR001347; KEGG: psl:Psta_0845 KpsF/GutQ family protein; PFAM: sugar isomerase (SIS); CBS domain containing protein; PRIAM: Arabinose-5-phosphate isomerase; SPTR: KpsF/GutQ family protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain; SIS domain; TIGRFAM: KpsF/GutQ family protein. | acyl-(acyl-carrier-protein)--UDP-N-acetylglucosa mineO-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.854 |
| Isop_0131 | Isop_3496 | Isop_0131 | Isop_3496 | KpsF/GutQ family protein; COGs: COG0794 sugar phosphate isomerase involved in capsule formation; InterPro IPR000644: IPR004800: IPR018506: IPR001347; KEGG: psl:Psta_0845 KpsF/GutQ family protein; PFAM: sugar isomerase (SIS); CBS domain containing protein; PRIAM: Arabinose-5-phosphate isomerase; SPTR: KpsF/GutQ family protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain; SIS domain; TIGRFAM: KpsF/GutQ family protein. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.886 |
| Isop_0131 | Isop_3621 | Isop_0131 | Isop_3621 | KpsF/GutQ family protein; COGs: COG0794 sugar phosphate isomerase involved in capsule formation; InterPro IPR000644: IPR004800: IPR018506: IPR001347; KEGG: psl:Psta_0845 KpsF/GutQ family protein; PFAM: sugar isomerase (SIS); CBS domain containing protein; PRIAM: Arabinose-5-phosphate isomerase; SPTR: KpsF/GutQ family protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain; SIS domain; TIGRFAM: KpsF/GutQ family protein. | acyl-(acyl-carrier-protein)--UDP-N-acetylglucosa mineO-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.858 |
| Isop_0131 | lpxD | Isop_0131 | Isop_0319 | KpsF/GutQ family protein; COGs: COG0794 sugar phosphate isomerase involved in capsule formation; InterPro IPR000644: IPR004800: IPR018506: IPR001347; KEGG: psl:Psta_0845 KpsF/GutQ family protein; PFAM: sugar isomerase (SIS); CBS domain containing protein; PRIAM: Arabinose-5-phosphate isomerase; SPTR: KpsF/GutQ family protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain; SIS domain; TIGRFAM: KpsF/GutQ family protein. | UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.880 |
| Isop_0131 | lpxK | Isop_0131 | Isop_1280 | KpsF/GutQ family protein; COGs: COG0794 sugar phosphate isomerase involved in capsule formation; InterPro IPR000644: IPR004800: IPR018506: IPR001347; KEGG: psl:Psta_0845 KpsF/GutQ family protein; PFAM: sugar isomerase (SIS); CBS domain containing protein; PRIAM: Arabinose-5-phosphate isomerase; SPTR: KpsF/GutQ family protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain; SIS domain; TIGRFAM: KpsF/GutQ family protein. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.893 |
| Isop_0227 | Isop_0346 | Isop_0227 | Isop_0346 | MotA/TolQ/ExbB proton channel; COGs: COG0811 Biopolymer transport protein; InterPro IPR002898; KEGG: plm:Plim_0746 MotA/TolQ/ExbB proton channel; PFAM: MotA/TolQ/ExbB proton channel; SPTR: MotA/TolQ/ExbB proton channel; PFAM: MotA/TolQ/ExbB proton channel family. | Permease YjgP/YjgQ family protein; COGs: COG0795 permease; InterPro IPR005495; KEGG: plm:Plim_2512 permease YjgP/YjgQ family protein; PFAM: permease YjgP/YjgQ family protein; SPTR: Permease YjgP/YjgQ family protein; PFAM: Predicted permease YjgP/YjgQ family. | 0.551 |
| Isop_0227 | Isop_0734 | Isop_0227 | Isop_0734 | MotA/TolQ/ExbB proton channel; COGs: COG0811 Biopolymer transport protein; InterPro IPR002898; KEGG: plm:Plim_0746 MotA/TolQ/ExbB proton channel; PFAM: MotA/TolQ/ExbB proton channel; SPTR: MotA/TolQ/ExbB proton channel; PFAM: MotA/TolQ/ExbB proton channel family. | ABC transporter related protein; COGs: COG1137 ABC-type (unclassified) transport system ATPase component; InterPro IPR003439: IPR003593: IPR017871; KEGG: psl:Psta_0620 ABC transporter related protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related protein; PFAM: ABC transporter. | 0.680 |
| Isop_0227 | Isop_0751 | Isop_0227 | Isop_0751 | MotA/TolQ/ExbB proton channel; COGs: COG0811 Biopolymer transport protein; InterPro IPR002898; KEGG: plm:Plim_0746 MotA/TolQ/ExbB proton channel; PFAM: MotA/TolQ/ExbB proton channel; SPTR: MotA/TolQ/ExbB proton channel; PFAM: MotA/TolQ/ExbB proton channel family. | acyl-(acyl-carrier-protein)--UDP-N-acetylglucosa mineO-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.598 |
| Isop_0227 | Isop_3496 | Isop_0227 | Isop_3496 | MotA/TolQ/ExbB proton channel; COGs: COG0811 Biopolymer transport protein; InterPro IPR002898; KEGG: plm:Plim_0746 MotA/TolQ/ExbB proton channel; PFAM: MotA/TolQ/ExbB proton channel; SPTR: MotA/TolQ/ExbB proton channel; PFAM: MotA/TolQ/ExbB proton channel family. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.643 |
| Isop_0227 | Isop_3621 | Isop_0227 | Isop_3621 | MotA/TolQ/ExbB proton channel; COGs: COG0811 Biopolymer transport protein; InterPro IPR002898; KEGG: plm:Plim_0746 MotA/TolQ/ExbB proton channel; PFAM: MotA/TolQ/ExbB proton channel; SPTR: MotA/TolQ/ExbB proton channel; PFAM: MotA/TolQ/ExbB proton channel family. | acyl-(acyl-carrier-protein)--UDP-N-acetylglucosa mineO-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.582 |
| Isop_0227 | lpxD | Isop_0227 | Isop_0319 | MotA/TolQ/ExbB proton channel; COGs: COG0811 Biopolymer transport protein; InterPro IPR002898; KEGG: plm:Plim_0746 MotA/TolQ/ExbB proton channel; PFAM: MotA/TolQ/ExbB proton channel; SPTR: MotA/TolQ/ExbB proton channel; PFAM: MotA/TolQ/ExbB proton channel family. | UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.553 |
| Isop_0227 | lpxK | Isop_0227 | Isop_1280 | MotA/TolQ/ExbB proton channel; COGs: COG0811 Biopolymer transport protein; InterPro IPR002898; KEGG: plm:Plim_0746 MotA/TolQ/ExbB proton channel; PFAM: MotA/TolQ/ExbB proton channel; SPTR: MotA/TolQ/ExbB proton channel; PFAM: MotA/TolQ/ExbB proton channel family. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.510 |
| Isop_0346 | Isop_0227 | Isop_0346 | Isop_0227 | Permease YjgP/YjgQ family protein; COGs: COG0795 permease; InterPro IPR005495; KEGG: plm:Plim_2512 permease YjgP/YjgQ family protein; PFAM: permease YjgP/YjgQ family protein; SPTR: Permease YjgP/YjgQ family protein; PFAM: Predicted permease YjgP/YjgQ family. | MotA/TolQ/ExbB proton channel; COGs: COG0811 Biopolymer transport protein; InterPro IPR002898; KEGG: plm:Plim_0746 MotA/TolQ/ExbB proton channel; PFAM: MotA/TolQ/ExbB proton channel; SPTR: MotA/TolQ/ExbB proton channel; PFAM: MotA/TolQ/ExbB proton channel family. | 0.551 |
| Isop_0346 | Isop_0347 | Isop_0346 | Isop_0347 | Permease YjgP/YjgQ family protein; COGs: COG0795 permease; InterPro IPR005495; KEGG: plm:Plim_2512 permease YjgP/YjgQ family protein; PFAM: permease YjgP/YjgQ family protein; SPTR: Permease YjgP/YjgQ family protein; PFAM: Predicted permease YjgP/YjgQ family. | Permease YjgP/YjgQ family protein; COGs: COG0795 permease; InterPro IPR005495; KEGG: psl:Psta_2358 permease YjgP/YjgQ family protein; PFAM: permease YjgP/YjgQ family protein; SPTR: Permease YjgP/YjgQ family protein; PFAM: Predicted permease YjgP/YjgQ family. | 0.933 |
| Isop_0346 | Isop_0734 | Isop_0346 | Isop_0734 | Permease YjgP/YjgQ family protein; COGs: COG0795 permease; InterPro IPR005495; KEGG: plm:Plim_2512 permease YjgP/YjgQ family protein; PFAM: permease YjgP/YjgQ family protein; SPTR: Permease YjgP/YjgQ family protein; PFAM: Predicted permease YjgP/YjgQ family. | ABC transporter related protein; COGs: COG1137 ABC-type (unclassified) transport system ATPase component; InterPro IPR003439: IPR003593: IPR017871; KEGG: psl:Psta_0620 ABC transporter related protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related protein; PFAM: ABC transporter. | 0.971 |
| Isop_0346 | Isop_0751 | Isop_0346 | Isop_0751 | Permease YjgP/YjgQ family protein; COGs: COG0795 permease; InterPro IPR005495; KEGG: plm:Plim_2512 permease YjgP/YjgQ family protein; PFAM: permease YjgP/YjgQ family protein; SPTR: Permease YjgP/YjgQ family protein; PFAM: Predicted permease YjgP/YjgQ family. | acyl-(acyl-carrier-protein)--UDP-N-acetylglucosa mineO-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.504 |
| Isop_0346 | Isop_3330 | Isop_0346 | Isop_3330 | Permease YjgP/YjgQ family protein; COGs: COG0795 permease; InterPro IPR005495; KEGG: plm:Plim_2512 permease YjgP/YjgQ family protein; PFAM: permease YjgP/YjgQ family protein; SPTR: Permease YjgP/YjgQ family protein; PFAM: Predicted permease YjgP/YjgQ family. | MotA/TolQ/ExbB proton channel; COGs: COG0811 Biopolymer transport protein; InterPro IPR002898; KEGG: plm:Plim_3807 MotA/TolQ/ExbB proton channel; PFAM: MotA/TolQ/ExbB proton channel; SPTR: Probable tolQ protein; PFAM: MotA/TolQ/ExbB proton channel family. | 0.490 |
| Isop_0346 | Isop_3496 | Isop_0346 | Isop_3496 | Permease YjgP/YjgQ family protein; COGs: COG0795 permease; InterPro IPR005495; KEGG: plm:Plim_2512 permease YjgP/YjgQ family protein; PFAM: permease YjgP/YjgQ family protein; SPTR: Permease YjgP/YjgQ family protein; PFAM: Predicted permease YjgP/YjgQ family. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.551 |
| Isop_0346 | Isop_3621 | Isop_0346 | Isop_3621 | Permease YjgP/YjgQ family protein; COGs: COG0795 permease; InterPro IPR005495; KEGG: plm:Plim_2512 permease YjgP/YjgQ family protein; PFAM: permease YjgP/YjgQ family protein; SPTR: Permease YjgP/YjgQ family protein; PFAM: Predicted permease YjgP/YjgQ family. | acyl-(acyl-carrier-protein)--UDP-N-acetylglucosa mineO-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.448 |