STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_0737Aldose 1-epimerase; COGs: COG2017 Galactose mutarotase; InterPro IPR008183; KEGG: plm:Plim_0702 aldose 1-epimerase; PFAM: Aldose 1-epimerase; SPTR: Aldose 1-epimerase; PFAM: Aldose 1-epimerase. (334 aa)    
Predicted Functional Partners:
Isop_0502
Galactokinase; COGs: COG0153 Galactokinase; InterProIPR019539: IPR006204: IPR013750: IPR000705: IPR 006203: IPR006206; KEGG: rrs:RoseRS_3819 galactokinase; PFAM: Galactokinase galactose-binding domain; GHMP kinase; GHMP kinase domain protein; SPTR: Galactokinase; TIGRFAM: galactokinase; PFAM: Galactokinase galactose-binding signature; GHMP kinases C terminal; GHMP kinases N terminal domain; TIGRFAM: galactokinase; Belongs to the GHMP kinase family. GalK subfamily.
 
 0.982
Isop_0741
ROK family protein; COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600: IPR002731; KEGG: psl:Psta_4719 ROK family protein; PFAM: ROK family protein; ATPase BadF/BadG/BcrA/BcrD type; SPTR: Glucokinase; PFAM: ROK family; TIGRFAM: ROK family protein (putative glucokinase).
    
 0.908
Isop_0829
ROK family protein; COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: plm:Plim_1388 ROK family protein; PFAM: ROK family protein; SPTR: ROK protein; PFAM: ROK family.
    
 0.908
Isop_2979
ROK family protein; COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: plm:Plim_2404 ROK family protein; PFAM: ROK family protein; SPTR: ROK family protein; manually curated; PFAM: ROK family; TIGRFAM: ROK family protein (putative glucokinase).
    
 0.908
Isop_0707
HAD-superfamily hydrolase, subfamily IA, variant 3; COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR005833: IPR005834: IPR006402; KEGG: spe:Spro_4879 phosphatase; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: HAD-superfamily hydrolase, subfamily IA, variant 3; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Epoxide hydrolase N-terminal domain-like phosphatase.
   
 
  0.901
Isop_1551
COGs: COG1085 Galactose-1-phosphate uridylyltransferase; InterPro IPR001937; KEGG: nde:NIDE3393 galactose-1-phosphate uridylyltransferase; PRIAM: UDP-glucose--hexose-1-phosphate uridylyltransferase; SPTR: Galactose-1-phosphate uridylyltransferase; PFAM: Galactose-1-phosphate uridyl transferase, N-terminal domain; TIGRFAM: galactose-1-phosphate uridylyltransferase, family 1.
  
 
 0.481
Isop_0287
Amidohydrolase 2; COGs: COG1904 Glucuronate isomerase; KEGG: plm:Plim_2160 amidohydrolase 2; SPTR: Putative uncharacterized protein; PFAM: Glucuronate isomerase.
 
     0.440
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.