STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_0749InterPro IPR005632; KEGG: plm:Plim_0920 outer membrane chaperone Skp (OmpH); PFAM: outer membrane chaperone Skp (OmpH); SPTR: Outer membrane chaperone Skp (OmpH); PFAM: Outer membrane protein (OmpH-like). (237 aa)    
Predicted Functional Partners:
Isop_1429
COGs: COG4775 Outer membrane protein/protective antigen OMA87; InterPro IPR016474: IPR010827: IPR000184; KEGG: plm:Plim_2365 outer membrane protein assembly complex, YaeT protein; PFAM: surface antigen (D15); surface antigen variable number repeat-containing protein; SPTR: Outer membrane protein assembly complex, YaeT protein; TIGRFAM: outer membrane protein assembly complex, YaeT protein; PFAM: Surface antigen variable number repeat; Surface antigen; TIGRFAM: outer membrane protein assembly complex, YaeT protein.
  
  
 0.718
lpxC
Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the thioester dehydratase family. FabZ subfamily.
  
    0.669
lpxD
UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
  
    0.665
rpmJ
LSU ribosomal protein L36P; InterPro IPR000473; KEGG: ele:Elen_2808 ribosomal protein L36; PFAM: ribosomal protein L36; SPTR: 50S ribosomal protein L36; TIGRFAM: ribosomal protein L36; PFAM: Ribosomal protein L36; TIGRFAM: ribosomal protein L36, bacterial type; Belongs to the bacterial ribosomal protein bL36 family.
   
    0.596
rpsM
SSU ribosomal protein S13P; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family.
   
    0.594
Isop_1312
COGs: COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair; InterPro IPR017963: IPR001126; KEGG: psl:Psta_3727 DNA-directed DNA polymerase; PFAM: UMUC domain protein DNA-repair protein; PRIAM: DNA-directed DNA polymerase; SPTR: DNA-directed DNA polymerase; PFAM: impB/mucB/samB family.
    
   0.567
Isop_2527
KEGG: hoh:Hoch_6408 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: SpoIVB peptidase S55.
  
    0.559
Isop_3190
Peptidase M50; COGs: COG0750 membrane-associated Zn-dependent protease 1; InterPro IPR001478: IPR008915; KEGG: plm:Plim_3363 peptidase M50; PFAM: peptidase M50; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; SPTR: Peptidase M50; PFAM: Peptidase family M50; PDZ domain (Also known as DHR or GLGF); TIGRFAM: RIP metalloprotease RseP.
  
  
 0.552
rpsF
Ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
  
    0.535
Isop_0751
acyl-(acyl-carrier-protein)--UDP-N-acetylglucosa mineO-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
  
  
 0.504
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.