STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Isop_0794Small GTP-binding protein; COGs: COG1163 GTPase; InterPro IPR006073: IPR002917: IPR004095: IPR005225; KEGG: psl:Psta_1013 GTP-binding protein HSR1-related protein; PFAM: GTP-binding protein HSR1-related; TGS domain-containing protein; SPTR: GTP-binding protein HSR1-related protein; TIGRFAM: small GTP-binding protein; PFAM: GTPase of unknown function; TGS domain; TIGRFAM: small GTP-binding protein domain. (332 aa)    
Predicted Functional Partners:
rpsC
SSU ribosomal protein S3P; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.
   
   0.722
rplJ
Ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.
  
   0.674
rplB
LSU ribosomal protein L2P; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
   
 
 0.664
rplW
LSU ribosomal protein L23P; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.
   
   0.614
rpsS
SSU ribosomal protein S19P; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
   
   0.610
rplR
LSU ribosomal protein L18P; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
   
   0.607
Isop_0863
Late embryogenesis abundant protein; InterPro IPR004238; KEGG: mgr:MGG_06862 hypothetical protein; PFAM: Late embryogenesis abundant protein; SPTR: Putative uncharacterized protein; PFAM: Late embryogenesis abundant protein.
   
   0.581
rplD
Ribosomal protein L4/L1e; Forms part of the polypeptide exit tunnel.
   
   0.581
Isop_0795
ATP-binding region ATPase domain protein; InterPro IPR003594: IPR016160; KEGG: sus:Acid_7798 response regulator receiver protein; PFAM: ATP-binding region ATPase domain protein; SPTR: Response regulator receiver protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
       0.551
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
    0.537
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.