Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_0805KEGG: scl:sce5120 protein kinase; SPTR: Serine/threonine protein kinase. (227 aa)    
Predicted Functional Partners:
Isop_0804
Protein serine phosphatase with GAF(s) sensor(s); COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR000253: IPR003018: IPR010822: IPR001932; KEGG: nhl:Nhal_1223 stage II sporulation E family protein; PFAM: Stage II sporulation protein E; GAF domain protein; Forkhead-associated protein; SMART: protein phosphatase 2C domain protein; GAF domain protein; Forkhead-associated protein; SPTR: Stage II sporulation E family protein; PFAM: GAF domain; Stage II sporulation protein E (SpoIIE); FHA domain.
   
 
 0.601
Isop_3151
Peptidase M56 BlaR1; InterPro IPR008756; KEGG: sus:Acid_5553 peptidase M56, BlaR1; PFAM: peptidase M56 BlaR1; SPTR: Peptidase M56, BlaR1.
  
     0.599
Isop_2897
KEGG: mxa:MXAN_7038 hypothetical protein; SPTR: Putative uncharacterized protein.
  
    0.511
Isop_2196
KEGG: mtp:Mthe_1075 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.481
Isop_1461
Hypothetical protein; KEGG: mca:MCA2974 PKD domain-containing protein; SPTR: PKD domain protein.
  
    0.463
Isop_1772
KEGG: hoh:Hoch_4942 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.462
Isop_1372
Dipeptidyl-peptidase 7; Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.
  
     0.452
Isop_2736
KEGG: mxa:MXAN_5625 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.448
Isop_0806
KEGG: rba:RB12189 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.438
Isop_2859
Hypothetical protein; InterPro IPR019734: IPR013026; KEGG: psl:Psta_2415 tetratricopeptide TPR_2 repeat protein; SPTR: Tetratricopeptide TPR_2 repeat protein.
 
     0.429
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
Server load: low (38%) [HD]