STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_0815Cysteine desulfurase IscS; COGs: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase; InterPro IPR000192: IPR016454; KEGG: cre:CHLREDRAFT_191269 cysteine desulfurase; PFAM: aminotransferase class V; PRIAM: Cysteine desulfurase; SPTR: Cysteine desulfurase; PFAM: Aminotransferase class-V. (426 aa)    
Predicted Functional Partners:
Isop_1969
Nitrogen-fixing NifU domain protein; COGs: COG0822 NifU homolog involved in Fe-S cluster formation; InterPro IPR002871; KEGG: plm:Plim_1321 nitrogen-fixing NifU domain protein; PFAM: nitrogen-fixing NifU domain protein; SPTR: Nitrogen-fixing NifU domain protein; PFAM: NifU-like N terminal domain; TIGRFAM: SUF system FeS assembly protein, NifU family.
 
 0.971
Isop_1342
UBA/THIF-type NAD/FAD binding protein; COGs: COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2; InterPro IPR000594; KEGG: psl:Psta_4146 UBA/ThiF-type NAD/FAD binding protein; PFAM: UBA/THIF-type NAD/FAD binding protein; SPTR: UBA/THIF-type NAD/FAD binding protein; PFAM: ThiF family.
   
 0.945
Isop_1376
UBA/THIF-type NAD/FAD binding protein; COGs: COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2; InterPro IPR000594: IPR007901; KEGG: sti:Sthe_0801 UBA/ThiF-type NAD/FAD binding protein; PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; SPTR: Molybdopterin biosynthesis protein MoeB; PFAM: MoeZ/MoeB domain; ThiF family.
   
 0.945
Isop_1999
Rhodanese domain protein; COGs: COG2897 Rhodanese-related sulfurtransferase; InterPro IPR001763: IPR001307; KEGG: pfl:PFL_0553 fused rhodanese domain-containing protein/phosphatidylserine decarboxylase; PFAM: Rhodanese domain protein; SMART: Rhodanese domain protein; SPTR: Rhodanese domain protein/phosphatidylserine decarboxylase; manually curated; PFAM: Rhodanese-like domain.
   
 0.912
Isop_2069
Rhodanese domain protein; COGs: COG2897 Rhodanese-related sulfurtransferase; InterPro IPR001763: IPR001307; KEGG: rxy:Rxyl_2802 thiosulfate sulfurtransferase; PFAM: Rhodanese domain protein; SMART: Rhodanese domain protein; SPTR: Thiosulfate sulfurtransferase; PFAM: Rhodanese-like domain.
   
 0.912
Isop_3229
COGs: COG2897 Rhodanese-related sulfurtransferase; InterPro IPR001307: IPR001763; KEGG: rmr:Rmar_0983 rhodanese domain protein; PFAM: Rhodanese domain protein; PRIAM: Thiosulfate sulfurtransferase; SMART: Rhodanese domain protein; SPTR: Rhodanese domain protein; PFAM: Rhodanese-like domain.
   
 0.912
Isop_2132
COGs: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase; InterPro IPR016454: IPR000192; KEGG: rmr:Rmar_1215 aminotransferase class V; PFAM: aminotransferase class V; PRIAM: Cysteine desulfurase; SPTR: Aminotransferase class V; PFAM: Aminotransferase class-V.
  
  
 
0.911
Isop_2222
Ferredoxin; COGs: COG0633 Ferredoxin; InterPro IPR001055: IPR001041; KEGG: cyt:cce_2108 ferredoxin; PFAM: ferredoxin; SPTR: Probable ferredoxin; PFAM: 2Fe-2S iron-sulfur cluster binding domain.
 
 0.846
Isop_3663
Iron-sulfur cluster assembly accessory protein; COGs: COG0316 conserved hypothetical protein; InterPro IPR017870: IPR000361: IPR016092; KEGG: plm:Plim_2978 iron-sulfur cluster assembly accessory protein; PFAM: HesB/YadR/YfhF-family protein; SPTR: Iron-sulfur cluster assembly accessory protein; TIGRFAM: iron-sulfur cluster assembly accessory protein; PFAM: Iron-sulphur cluster biosynthesis; TIGRFAM: Iron-sulfur cluster assembly accessory protein; Belongs to the HesB/IscA family.
 
 
 0.783
selD
Selenide, water dikinase; Synthesizes selenophosphate from selenide and ATP.
  
 
 0.667
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.