STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Isop_0826Hypothetical protein; KEGG: pca:Pcar_1265 putative LPS biosynthesis enzyme; SPTR: Mn2+-dependent serine/threonine protein kinase; PFAM: Lipopolysaccharide kinase (Kdo/WaaP) family. (302 aa)    
Predicted Functional Partners:
Isop_0825
COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: sfu:Sfum_0373 glycosyl transferase, group 1; PFAM: glycosyl transferase group 1; SPTR: Probable glycosyltransferase; PFAM: Glycosyl transferases group 1.
 
  
  0.981
Isop_1281
Lipopolysaccharide heptosyltransferase II; COGs: COG0859 ADP-heptose:LPS heptosyltransferase; InterPro IPR011910: IPR002201; KEGG: plm:Plim_0899 lipopolysaccharide heptosyltransferase II; PFAM: glycosyl transferase family 9; SPTR: ADP-heptose--LPS heptosyltransferase II, putative; TIGRFAM: lipopolysaccharide heptosyltransferase II; PFAM: Glycosyltransferase family 9 (heptosyltransferase); TIGRFAM: lipopolysaccharide heptosyltransferase II.
 
 
  0.932
Isop_2778
Three-deoxy-D-manno-octulosonic-acid transferase domain-containing protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.
    
 0.900
Isop_0827
KEGG: tcx:Tcr_2091 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.781
Isop_2566
Hypothetical protein; InterPro IPR008271; KEGG: plm:Plim_0617 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Lipopolysaccharide kinase (Kdo/WaaP) family.
  
     0.772
Isop_0824
Nucleotidyl transferase; COGs: COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon); InterPro IPR005835; KEGG: rrs:RoseRS_4077 nucleotidyl transferase; PFAM: Nucleotidyl transferase; SPTR: Nucleotidyl transferase; PFAM: Nucleotidyl transferase.
  
 
 0.753
Isop_3277
KEGG: nha:Nham_2630 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF2029).
  
    0.753
Isop_0235
PDZ/DHR/GLGF domain protein; InterPro IPR001478; KEGG: ote:Oter_4030 PDZ/DHR/GLGF domain-containing protein; PFAM: PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; SPTR: PDZ/DHR/GLGF domain protein; PFAM: PDZ domain (Also known as DHR or GLGF).
  
     0.739
Isop_0236
PDZ/DHR/GLGF domain protein; InterPro IPR001478: IPR001969; KEGG: rlt:Rleg2_1589 membrane-associated zinc metalloprotease; PFAM: PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; SPTR: Membrane-associated zinc metalloprotease; PFAM: PDZ domain (Also known as DHR or GLGF).
  
     0.731
Isop_1111
Tyrosine phosphatase; InterPro IPR000387: IPR004861; KEGG: geo:Geob_0068 protein tyrosine/serine phosphatase; PFAM: tyrosine phosphatase; SPTR: Protein tyrosine/serine phosphatase; PFAM: Tyrosine phosphatase family.
  
     0.714
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.