STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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cysCSulfate adenylyltransferase; Catalyzes the synthesis of activated sulfate. (581 aa)    
Predicted Functional Partners:
cysH
Phosphoadenylylsulfate reductase (thioredoxin); Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.
 0.999
Isop_1056
COGs: COG0155 Sulfite reductase beta subunit (hemoprotein); InterPro IPR005117: IPR006067: IPR006066; KEGG: psl:Psta_1330 sulfite reductase (NADPH); PFAM: nitrite and sulphite reductase 4Fe-4S region; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; PRIAM: Sulfite reductase (NADPH); SPTR: Sulfite reductase; PFAM: Nitrite and sulphite reductase 4Fe-4S domain; Nitrite/Sulfite reductase ferredoxin-like half domain; TIGRFAM: ferredoxin-sulfite reductase.
 
  
 0.991
cysA
Sulfate ABC transporter, ATPase subunit; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system.
  
 
 0.988
Isop_1503
COGs: COG1613 ABC-type sulfate transport system periplasmic component; InterPro IPR005669; KEGG: gym:GYMC10_5202 sulfate ABC transporter, periplasmic sulfate-binding protein; SPTR: Sulfate ABC transporter, periplasmic sulfate-binding protein; TIGRFAM: sulfate ABC transporter, periplasmic sulfate-binding protein; TIGRFAM: sulfate/thiosulfate-binding protein.
  
 
 0.988
Isop_1501
Sulfate ABC transporter, inner membrane subunit; COGs: COG4208 ABC-type sulfate transport system permease component; InterPro IPR000515: IPR005667; KEGG: cya:CYA_0468 sulfate ABC transporter, permease protein CysW; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Sulfate ABC transporter, permease protein CysW; TIGRFAM: sulfate ABC transporter, inner membrane subunit; PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: sulfate ABC transporter, permease protein CysW; sulfate ABC transporter, permease protein.
  
 
 0.987
Isop_1502
Sulfate ABC transporter, inner membrane subunit; COGs: COG0555 ABC-type sulfate transport system permease component; InterPro IPR000515: IPR005667; KEGG: hau:Haur_0258 sulfate ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Sulfate ABC transporter, inner membrane subunit; TIGRFAM: sulfate ABC transporter, inner membrane subunit; PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: sulfate ABC transporter, permease protein CysW; sulfate ABC transporter, permease protein; sulfate ABC [...]
  
 
 0.986
Isop_3300
uroporphyrin-III C-methyltransferase; COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR003043: IPR006366: IPR000878: IPR003754; KEGG: gme:Gmet_3235 uroporphyrinogen-III synthase/uroporphyrinogen-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: Uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase.
 
  
 0.959
Isop_1528
Oxidoreductase FAD/NAD(P)-binding domain protein; COGs: COG0369 Sulfite reductase alpha subunit (flavoprotein); InterProIPR017927: IPR001709: IPR012146: IPR008333: IPR 001433; KEGG: gvi:gvip312 ferredoxin--NADP+ reductase; PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; SPTR: Ferredoxin--NADP+ reductase; manually curated; PFAM: Oxidoreductase FAD-binding domain; Oxidoreductase NAD-binding domain.
  
  
 0.954
Isop_3051
Phosphoesterase RecJ domain protein; COGs: COG0618 Exopolyphosphatase-related protein; InterPro IPR001667: IPR003156; KEGG: plm:Plim_0422 phosphoesterase RecJ domain protein; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; SPTR: Phosphoesterase RecJ domain protein; PFAM: DHHA1 domain; DHH family.
    
  0.901
Isop_2720
Histidine triad (HIT) protein; COGs: COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolase; InterPro IPR001310; KEGG: dau:Daud_1871 histidine triad (HIT) protein; PFAM: histidine triad (HIT) protein; SPTR: Histidine triad (HIT) protein; PFAM: HIT domain.
    
  0.900
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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