Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_0851Anti-anti-sigma factor; InterPro IPR002645: IPR003658; KEGG: plm:Plim_0153 anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; SPTR: Putative uncharacterized protein; TIGRFAM: anti-anti-sigma factor; PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor. (124 aa)    
Predicted Functional Partners:
Isop_2636
Protein serine/threonine phosphatase; COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR010822: IPR003594: IPR001932; KEGG: cli:Clim_1832 putative PAS/PAC sensor protein; PFAM: Stage II sporulation protein E; ATP-binding region ATPase domain protein; SMART: protein phosphatase 2C domain protein; SPTR: Putative PAS/PAC sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Stage II sporulation protein E (SpoIIE).
  
 
 0.949
Isop_0853
GCN5-related N-acetyltransferase; InterPro IPR000182; KEGG: srm:SRM_03016 acetyltransferase, GNAT family; PFAM: GCN5-related N-acetyltransferase; SPTR: Acetyltransferase, GNAT family; PFAM: Acetyltransferase (GNAT) family.
 
     0.805
Isop_0795
ATP-binding region ATPase domain protein; InterPro IPR003594: IPR016160; KEGG: sus:Acid_7798 response regulator receiver protein; PFAM: ATP-binding region ATPase domain protein; SPTR: Response regulator receiver protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
 
 0.781
Isop_0852
Rhomboid family protein; COGs: COG0705 membrane protein; InterPro IPR002610; KEGG: mmh:Mmah_1165 rhomboid family protein; PFAM: Rhomboid family protein; SPTR: Cytoplasmic membrane protein; PFAM: Rhomboid family.
       0.773
Isop_3147
COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR003594; KEGG: sus:Acid_7798 response regulator receiver protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; SMART: response regulator receiver; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
  
 
 0.761
Isop_3271
COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358: IPR000014: IPR001610: IPR003661: IPR 003594: IPR001789: IPR005467: IPR000700: IPR008207: IPR013767; KEGG: psl:Psta_1412 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; PAC repeat-containing protein; response regulator receiver; SPTR: PAS/PAC sensor hybrid h [...]
  
  
 0.752
Isop_0267
Flagellar P-ring protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
  
    0.746
Isop_0804
Protein serine phosphatase with GAF(s) sensor(s); COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR000253: IPR003018: IPR010822: IPR001932; KEGG: nhl:Nhal_1223 stage II sporulation E family protein; PFAM: Stage II sporulation protein E; GAF domain protein; Forkhead-associated protein; SMART: protein phosphatase 2C domain protein; GAF domain protein; Forkhead-associated protein; SPTR: Stage II sporulation E family protein; PFAM: GAF domain; Stage II sporulation protein E (SpoIIE); FHA domain.
 
 
 0.739
Isop_3070
InterPro IPR011465; KEGG: plm:Plim_3142 protein of unknown function DUF1571; PFAM: protein of unknown function DUF1571; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1571).
  
     0.736
Isop_0287
Amidohydrolase 2; COGs: COG1904 Glucuronate isomerase; KEGG: plm:Plim_2160 amidohydrolase 2; SPTR: Putative uncharacterized protein; PFAM: Glucuronate isomerase.
  
     0.732
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.