STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_0852Rhomboid family protein; COGs: COG0705 membrane protein; InterPro IPR002610; KEGG: mmh:Mmah_1165 rhomboid family protein; PFAM: Rhomboid family protein; SPTR: Cytoplasmic membrane protein; PFAM: Rhomboid family. (406 aa)    
Predicted Functional Partners:
Isop_0853
GCN5-related N-acetyltransferase; InterPro IPR000182; KEGG: srm:SRM_03016 acetyltransferase, GNAT family; PFAM: GCN5-related N-acetyltransferase; SPTR: Acetyltransferase, GNAT family; PFAM: Acetyltransferase (GNAT) family.
       0.780
Isop_0851
Anti-anti-sigma factor; InterPro IPR002645: IPR003658; KEGG: plm:Plim_0153 anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; SPTR: Putative uncharacterized protein; TIGRFAM: anti-anti-sigma factor; PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor.
       0.773
Isop_0687
InterPro IPR003369; KEGG: plm:Plim_2724 twin-arginine translocation protein, TatA/E family subunit; PFAM: sec-independent translocation protein mttA/Hcf106; SPTR: Putative Sec-independent protein translocase component; PFAM: mttA/Hcf106 family; TIGRFAM: twin arginine-targeting protein translocase, TatA/E family.
   
 
 0.468
tatA
Twin-arginine translocation protein, TatA/E family subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
   
 
 0.468
Isop_0850
KEGG: plm:Plim_2412 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.455
Isop_2833
COGs: COG0212 5-formyltetrahydrofolate cyclo-ligase; InterPro IPR002698; KEGG: rxy:Rxyl_1321 5-formyltetrahydrofolate cyclo-ligase; PFAM: 5-formyltetrahydrofolate cyclo-ligase; SPTR: 5-formyltetrahydrofolate cyclo-ligase; TIGRFAM: 5-formyltetrahydrofolate cyclo-ligase; manually curated; PFAM: 5-formyltetrahydrofolate cyclo-ligase family; TIGRFAM: 5,10-methenyltetrahydrofolate synthetase.
  
  
 0.433
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.