STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
trmBtRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (261 aa)    
Predicted Functional Partners:
Isop_1776
tRNA pseudouridine synthase D TruD; COGs: COG0585 conserved hypothetical protein; InterPro IPR011760: IPR020119: IPR001656; KEGG: plm:Plim_3118 tRNA pseudouridine synthase D TruD; PFAM: tRNA pseudouridine synthase D TruD; SPTR: tRNA pseudouridine synthase D TruD; PFAM: tRNA pseudouridine synthase D (TruD); TIGRFAM: tRNA pseudouridine synthase, TruD family.
 
 
 0.802
truB
tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
  
 
 0.730
Isop_2331
Fmu (Sun) domain protein; COGs: COG0144 tRNA and rRNA cytosine-C5-methylase; InterPro IPR001678; KEGG: shw:Sputw3181_2798 Fmu (Sun) domain-containing protein; PFAM: Fmu (Sun) domain protein; SPTR: NOL1/NOP2/sun family putative RNA methylase; PFAM: NOL1/NOP2/sun family; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
   
 
 0.690
Isop_1071
rRNA methylase; InterPro IPR010719; KEGG: rmr:Rmar_1203 putative rRNA methylase; PFAM: rRNA methylase; SPTR: Putative rRNA methylase; PFAM: Putative rRNA methylase.
  
 
 0.681
Isop_0858
Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ; COGs: COG0764 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase; InterPro IPR013114; KEGG: plm:Plim_3297 beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ; PFAM: Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ; SPTR: Beta-hydroxyacyl-(Acyl-carrier-protein) dehydratase FabA/FabZ; PFAM: FabA-like domain.
 
     0.606
tilS
tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.
   
  
 0.515
rsmG
Methyltransferase GidB; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
  
 
 0.498
Isop_0206
KEGG: cag:Cagg_3809 protein of unknown function DUF88; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function DUF88.
  
  
 0.490
Isop_1168
Methyltransferase FkbM family; InterPro IPR006342; KEGG: rru:Rru_A3719 methyltransferase FkbM; SPTR: Genome sequencing data, contig C315; TIGRFAM: methyltransferase FkbM family; TIGRFAM: methyltransferase, FkbM family.
   
  
 0.490
Isop_1808
KEGG: hoh:Hoch_4264 protein of unknown function DUF88; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function DUF88.
  
  
 0.490
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.