STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_0941COGs: COG1454 Alcohol dehydrogenase class IV; InterPro IPR001670: IPR017972; KEGG: reu:Reut_C6426 iron-containing alcohol dehydrogenase; PFAM: iron-containing alcohol dehydrogenase; SPTR: Iron-containing alcohol dehydrogenase; PFAM: Iron-containing alcohol dehydrogenase. (398 aa)    
Predicted Functional Partners:
Isop_1630
COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR012408: IPR015590; KEGG: plm:Plim_1751 aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: Ethanolamine utilization protein EutE; PFAM: Aldehyde dehydrogenase family.
 
 0.946
Isop_2885
Succinate semialdehyde dehydrogenase; COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR016160: IPR015590; KEGG: bts:Btus_0370 succinic semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: Succinic semialdehyde dehydrogenase; PFAM: Aldehyde dehydrogenase family; TIGRFAM: succinate-semialdehyde dehydrogenase.
 
 0.931
Isop_2345
COGs: COG0160 4-aminobutyrate aminotransferase and related aminotransferase; InterPro IPR005814: IPR004636; KEGG: cyc:PCC7424_4452 4-aminobutyrate aminotransferase; PFAM: aminotransferase class-III; PRIAM: Acetylornithine transaminase; SPTR: Acetylornithine transaminase; TIGRFAM: acetylornithine and succinylornithine aminotransferase; PFAM: Aminotransferase class-III; TIGRFAM: 4-aminobutyrate aminotransferase, prokaryotic type; acetylornithine and succinylornithine aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.913
Isop_0422
Alcohol dehydrogenase GroES domain protein; COGs: COG1064 Zn-dependent alcohol dehydrogenase; InterPro IPR013154: IPR013149: IPR002328; KEGG: rca:Rcas_4434 alcohol dehydrogenase; PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; SPTR: Alcohol dehydrogenase GroES domain protein; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase.
  
 
 0.820
Isop_0942
KEGG: rba:RB3171 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.773
glgA
Glycogen/starch synthase, ADP-glucose type; Synthesizes alpha-1,4-glucan chains using ADP-glucose.
   
    0.632
Isop_1385
Pyruvate formate-lyase activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family.
 
  
 0.630
Isop_1721
Radical SAM domain protein; COGs: COG1180 Pyruvate-formate lyase-activating enzyme; InterPro IPR012837: IPR007197; KEGG: mxa:MXAN_2901 radical SAM domain-containing protein; PFAM: Radical SAM domain protein; SPTR: Putative radical SAM domain protein; PFAM: Radical SAM superfamily.
 
  
 0.567
Isop_0940
Hypothetical protein; KEGG: gvi:gvip179 dihydrobiliverdin:ferredoxin oxidoreductase; SPTR: Ferredoxin-dependent bilin reductase; PFAM: Ferredoxin-dependent bilin reductase.
       0.532
Isop_1388
COGs: COG1882 Pyruvate-formate lyase; InterPro IPR001150: IPR005949: IPR004184: IPR019777; KEGG: cya:CYA_0477 formate acetyltransferase; PFAM: pyruvate formate-lyase PFL; formate C-acetyltransferase glycine radical; PRIAM: Formate C-acetyltransferase; SPTR: Formate acetyltransferase; TIGRFAM: formate acetyltransferase; PFAM: Glycine radical; Pyruvate formate lyase; TIGRFAM: formate acetyltransferase 1.
 
  
 0.494
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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