| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Isop_0235 | Isop_0943 | Isop_0235 | Isop_0943 | PDZ/DHR/GLGF domain protein; InterPro IPR001478; KEGG: ote:Oter_4030 PDZ/DHR/GLGF domain-containing protein; PFAM: PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; SPTR: PDZ/DHR/GLGF domain protein; PFAM: PDZ domain (Also known as DHR or GLGF). | COGs: COG3684 Tagatose-1 6-bisphosphate aldolase; InterPro IPR002915; KEGG: deb:DehaBAV1_1156 tagatose 1,6-diphosphate aldolase; PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; PRIAM: Tagatose-bisphosphate aldolase; SPTR: Tagatose-bisphosphate aldolase; PFAM: DeoC/LacD family aldolase; TIGRFAM: tagatose 1,6-diphosphate aldolase. | 0.720 |
| Isop_0235 | Isop_3277 | Isop_0235 | Isop_3277 | PDZ/DHR/GLGF domain protein; InterPro IPR001478; KEGG: ote:Oter_4030 PDZ/DHR/GLGF domain-containing protein; PFAM: PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; SPTR: PDZ/DHR/GLGF domain protein; PFAM: PDZ domain (Also known as DHR or GLGF). | KEGG: nha:Nham_2630 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF2029). | 0.763 |
| Isop_0943 | Isop_0235 | Isop_0943 | Isop_0235 | COGs: COG3684 Tagatose-1 6-bisphosphate aldolase; InterPro IPR002915; KEGG: deb:DehaBAV1_1156 tagatose 1,6-diphosphate aldolase; PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; PRIAM: Tagatose-bisphosphate aldolase; SPTR: Tagatose-bisphosphate aldolase; PFAM: DeoC/LacD family aldolase; TIGRFAM: tagatose 1,6-diphosphate aldolase. | PDZ/DHR/GLGF domain protein; InterPro IPR001478; KEGG: ote:Oter_4030 PDZ/DHR/GLGF domain-containing protein; PFAM: PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; SPTR: PDZ/DHR/GLGF domain protein; PFAM: PDZ domain (Also known as DHR or GLGF). | 0.720 |
| Isop_0943 | Isop_1019 | Isop_0943 | Isop_1019 | COGs: COG3684 Tagatose-1 6-bisphosphate aldolase; InterPro IPR002915; KEGG: deb:DehaBAV1_1156 tagatose 1,6-diphosphate aldolase; PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; PRIAM: Tagatose-bisphosphate aldolase; SPTR: Tagatose-bisphosphate aldolase; PFAM: DeoC/LacD family aldolase; TIGRFAM: tagatose 1,6-diphosphate aldolase. | PfkB domain protein; COGs: COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); InterPro IPR011611: IPR002173; KEGG: sth:STH1246 tagatose-6-phosphate kinase; PFAM: PfkB domain protein; SPTR: Tagatose-6-phosphate kinase; PFAM: pfkB family carbohydrate kinase; TIGRFAM: hexose kinase, 1-phosphofructokinase family. | 0.945 |
| Isop_0943 | Isop_1077 | Isop_0943 | Isop_1077 | COGs: COG3684 Tagatose-1 6-bisphosphate aldolase; InterPro IPR002915; KEGG: deb:DehaBAV1_1156 tagatose 1,6-diphosphate aldolase; PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; PRIAM: Tagatose-bisphosphate aldolase; SPTR: Tagatose-bisphosphate aldolase; PFAM: DeoC/LacD family aldolase; TIGRFAM: tagatose 1,6-diphosphate aldolase. | COGs: COG0205 6-phosphofructokinase; InterPro IPR011403: IPR000023; KEGG: psl:Psta_4392 6-phosphofructokinase; PFAM: phosphofructokinase; SPTR: 6-phosphofructokinase; PFAM: Phosphofructokinase. | 0.900 |
| Isop_0943 | Isop_2595 | Isop_0943 | Isop_2595 | COGs: COG3684 Tagatose-1 6-bisphosphate aldolase; InterPro IPR002915; KEGG: deb:DehaBAV1_1156 tagatose 1,6-diphosphate aldolase; PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; PRIAM: Tagatose-bisphosphate aldolase; SPTR: Tagatose-bisphosphate aldolase; PFAM: DeoC/LacD family aldolase; TIGRFAM: tagatose 1,6-diphosphate aldolase. | COGs: COG0205 6-phosphofructokinase; InterPro IPR000023; KEGG: plm:Plim_2681 phosphofructokinase; PFAM: phosphofructokinase; SPTR: 6-phosphofructokinase I; PFAM: Phosphofructokinase. | 0.900 |
| Isop_0943 | Isop_2935 | Isop_0943 | Isop_2935 | COGs: COG3684 Tagatose-1 6-bisphosphate aldolase; InterPro IPR002915; KEGG: deb:DehaBAV1_1156 tagatose 1,6-diphosphate aldolase; PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; PRIAM: Tagatose-bisphosphate aldolase; SPTR: Tagatose-bisphosphate aldolase; PFAM: DeoC/LacD family aldolase; TIGRFAM: tagatose 1,6-diphosphate aldolase. | COGs: COG2414 Aldehyde:ferredoxin oxidoreductase; InterPro IPR013983: IPR001203; KEGG: kfl:Kfla_2116 aldehyde ferredoxin oxidoreductase; PFAM: aldehyde ferredoxin oxidoreductase; Aldehyde ferredoxin oxidoreductase; PRIAM: Aldehyde ferredoxin oxidoreductase; SMART: Aldehyde ferredoxin oxidoreductase; SPTR: Aldehyde ferredoxin oxidoreductase; PFAM: Aldehyde ferredoxin oxidoreductase, N-terminal domain; Aldehyde ferredoxin oxidoreductase, domains 2 & 3. | 0.800 |
| Isop_0943 | Isop_2970 | Isop_0943 | Isop_2970 | COGs: COG3684 Tagatose-1 6-bisphosphate aldolase; InterPro IPR002915; KEGG: deb:DehaBAV1_1156 tagatose 1,6-diphosphate aldolase; PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; PRIAM: Tagatose-bisphosphate aldolase; SPTR: Tagatose-bisphosphate aldolase; PFAM: DeoC/LacD family aldolase; TIGRFAM: tagatose 1,6-diphosphate aldolase. | COGs: COG0205 6-phosphofructokinase; InterPro IPR000023: IPR012004; KEGG: psl:Psta_0329 diphosphate--fructose-6-phosphate1-phosphotransferase; PFAM: phosphofructokinase; SPTR:Diphosphate--fructose-6-phosphate1-phosphotran sferase; PFAM: Phosphofructokinase. | 0.900 |
| Isop_0943 | Isop_3277 | Isop_0943 | Isop_3277 | COGs: COG3684 Tagatose-1 6-bisphosphate aldolase; InterPro IPR002915; KEGG: deb:DehaBAV1_1156 tagatose 1,6-diphosphate aldolase; PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; PRIAM: Tagatose-bisphosphate aldolase; SPTR: Tagatose-bisphosphate aldolase; PFAM: DeoC/LacD family aldolase; TIGRFAM: tagatose 1,6-diphosphate aldolase. | KEGG: nha:Nham_2630 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF2029). | 0.742 |
| Isop_0943 | Isop_3401 | Isop_0943 | Isop_3401 | COGs: COG3684 Tagatose-1 6-bisphosphate aldolase; InterPro IPR002915; KEGG: deb:DehaBAV1_1156 tagatose 1,6-diphosphate aldolase; PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; PRIAM: Tagatose-bisphosphate aldolase; SPTR: Tagatose-bisphosphate aldolase; PFAM: DeoC/LacD family aldolase; TIGRFAM: tagatose 1,6-diphosphate aldolase. | COGs: COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase; InterPro IPR000887; KEGG: psl:Psta_4168 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase; SPTR: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; TIGRFAM: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase; TIGRFAM: Entner-Doudoroff aldolase. | 0.824 |
| Isop_0943 | pfp | Isop_0943 | Isop_3208 | COGs: COG3684 Tagatose-1 6-bisphosphate aldolase; InterPro IPR002915; KEGG: deb:DehaBAV1_1156 tagatose 1,6-diphosphate aldolase; PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; PRIAM: Tagatose-bisphosphate aldolase; SPTR: Tagatose-bisphosphate aldolase; PFAM: DeoC/LacD family aldolase; TIGRFAM: tagatose 1,6-diphosphate aldolase. | Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.900 |
| Isop_0943 | pfp-2 | Isop_0943 | Isop_3233 | COGs: COG3684 Tagatose-1 6-bisphosphate aldolase; InterPro IPR002915; KEGG: deb:DehaBAV1_1156 tagatose 1,6-diphosphate aldolase; PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; PRIAM: Tagatose-bisphosphate aldolase; SPTR: Tagatose-bisphosphate aldolase; PFAM: DeoC/LacD family aldolase; TIGRFAM: tagatose 1,6-diphosphate aldolase. | Pyrophosphate-dependent phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.900 |
| Isop_1019 | Isop_0943 | Isop_1019 | Isop_0943 | PfkB domain protein; COGs: COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); InterPro IPR011611: IPR002173; KEGG: sth:STH1246 tagatose-6-phosphate kinase; PFAM: PfkB domain protein; SPTR: Tagatose-6-phosphate kinase; PFAM: pfkB family carbohydrate kinase; TIGRFAM: hexose kinase, 1-phosphofructokinase family. | COGs: COG3684 Tagatose-1 6-bisphosphate aldolase; InterPro IPR002915; KEGG: deb:DehaBAV1_1156 tagatose 1,6-diphosphate aldolase; PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; PRIAM: Tagatose-bisphosphate aldolase; SPTR: Tagatose-bisphosphate aldolase; PFAM: DeoC/LacD family aldolase; TIGRFAM: tagatose 1,6-diphosphate aldolase. | 0.945 |
| Isop_1077 | Isop_0943 | Isop_1077 | Isop_0943 | COGs: COG0205 6-phosphofructokinase; InterPro IPR011403: IPR000023; KEGG: psl:Psta_4392 6-phosphofructokinase; PFAM: phosphofructokinase; SPTR: 6-phosphofructokinase; PFAM: Phosphofructokinase. | COGs: COG3684 Tagatose-1 6-bisphosphate aldolase; InterPro IPR002915; KEGG: deb:DehaBAV1_1156 tagatose 1,6-diphosphate aldolase; PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; PRIAM: Tagatose-bisphosphate aldolase; SPTR: Tagatose-bisphosphate aldolase; PFAM: DeoC/LacD family aldolase; TIGRFAM: tagatose 1,6-diphosphate aldolase. | 0.900 |
| Isop_2595 | Isop_0943 | Isop_2595 | Isop_0943 | COGs: COG0205 6-phosphofructokinase; InterPro IPR000023; KEGG: plm:Plim_2681 phosphofructokinase; PFAM: phosphofructokinase; SPTR: 6-phosphofructokinase I; PFAM: Phosphofructokinase. | COGs: COG3684 Tagatose-1 6-bisphosphate aldolase; InterPro IPR002915; KEGG: deb:DehaBAV1_1156 tagatose 1,6-diphosphate aldolase; PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; PRIAM: Tagatose-bisphosphate aldolase; SPTR: Tagatose-bisphosphate aldolase; PFAM: DeoC/LacD family aldolase; TIGRFAM: tagatose 1,6-diphosphate aldolase. | 0.900 |
| Isop_2595 | pfp-2 | Isop_2595 | Isop_3233 | COGs: COG0205 6-phosphofructokinase; InterPro IPR000023; KEGG: plm:Plim_2681 phosphofructokinase; PFAM: phosphofructokinase; SPTR: 6-phosphofructokinase I; PFAM: Phosphofructokinase. | Pyrophosphate-dependent phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.650 |
| Isop_2935 | Isop_0943 | Isop_2935 | Isop_0943 | COGs: COG2414 Aldehyde:ferredoxin oxidoreductase; InterPro IPR013983: IPR001203; KEGG: kfl:Kfla_2116 aldehyde ferredoxin oxidoreductase; PFAM: aldehyde ferredoxin oxidoreductase; Aldehyde ferredoxin oxidoreductase; PRIAM: Aldehyde ferredoxin oxidoreductase; SMART: Aldehyde ferredoxin oxidoreductase; SPTR: Aldehyde ferredoxin oxidoreductase; PFAM: Aldehyde ferredoxin oxidoreductase, N-terminal domain; Aldehyde ferredoxin oxidoreductase, domains 2 & 3. | COGs: COG3684 Tagatose-1 6-bisphosphate aldolase; InterPro IPR002915; KEGG: deb:DehaBAV1_1156 tagatose 1,6-diphosphate aldolase; PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; PRIAM: Tagatose-bisphosphate aldolase; SPTR: Tagatose-bisphosphate aldolase; PFAM: DeoC/LacD family aldolase; TIGRFAM: tagatose 1,6-diphosphate aldolase. | 0.800 |
| Isop_2970 | Isop_0943 | Isop_2970 | Isop_0943 | COGs: COG0205 6-phosphofructokinase; InterPro IPR000023: IPR012004; KEGG: psl:Psta_0329 diphosphate--fructose-6-phosphate1-phosphotransferase; PFAM: phosphofructokinase; SPTR:Diphosphate--fructose-6-phosphate1-phosphotran sferase; PFAM: Phosphofructokinase. | COGs: COG3684 Tagatose-1 6-bisphosphate aldolase; InterPro IPR002915; KEGG: deb:DehaBAV1_1156 tagatose 1,6-diphosphate aldolase; PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; PRIAM: Tagatose-bisphosphate aldolase; SPTR: Tagatose-bisphosphate aldolase; PFAM: DeoC/LacD family aldolase; TIGRFAM: tagatose 1,6-diphosphate aldolase. | 0.900 |
| Isop_3277 | Isop_0235 | Isop_3277 | Isop_0235 | KEGG: nha:Nham_2630 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF2029). | PDZ/DHR/GLGF domain protein; InterPro IPR001478; KEGG: ote:Oter_4030 PDZ/DHR/GLGF domain-containing protein; PFAM: PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; SPTR: PDZ/DHR/GLGF domain protein; PFAM: PDZ domain (Also known as DHR or GLGF). | 0.763 |
| Isop_3277 | Isop_0943 | Isop_3277 | Isop_0943 | KEGG: nha:Nham_2630 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF2029). | COGs: COG3684 Tagatose-1 6-bisphosphate aldolase; InterPro IPR002915; KEGG: deb:DehaBAV1_1156 tagatose 1,6-diphosphate aldolase; PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; PRIAM: Tagatose-bisphosphate aldolase; SPTR: Tagatose-bisphosphate aldolase; PFAM: DeoC/LacD family aldolase; TIGRFAM: tagatose 1,6-diphosphate aldolase. | 0.742 |