STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Isop_0962ATPase AAA-2 domain protein; COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterProIPR003593: IPR001943: IPR004176: IPR003959: IPR 013093: IPR019489: IPR001270: IPR018368; KEGG: plm:Plim_0603 ATPase AAA-2 domain protein; PFAM: ATPase AAA-2 domain protein; Clp domain protein; AAA ATPase central domain protein; UvrB/UvrC protein; Clp ATPase-like; SMART: AAA ATPase; SPTR: ATPase AAA-2 domain protein; PFAM: AAA domain (Cdc48 subfamily); Clp amino terminal domain; C-terminal, D2-small domain, of ClpB protein; ATPase family associated with various cellular activities (AAA [...] (844 aa)    
Predicted Functional Partners:
Isop_0076
Heat shock protein 70; COGs: COG0443 Molecular chaperone; InterPro IPR001023: IPR018181: IPR013126; KEGG: cac:CA_C0472 HSP70/DnaK family protein; PFAM: Heat shock protein 70; SPTR: Chaperone protein dnaK; PFAM: Hsp70 protein.
  
 
 0.752
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 
 0.752
Isop_1041
Heat shock protein 70; COGs: COG0443 Molecular chaperone; InterPro IPR002035: IPR013126: IPR001023: IPR018181; KEGG: cac:CA_C0473 heat shock protein DnaK; PFAM: Heat shock protein 70; von Willebrand factor type A; SMART: von Willebrand factor type A; SPTR: DnaK protein (Heat shock protein), C-terminal region has VWA type A domain; PFAM: Hsp70 protein; von Willebrand factor type A domain.
  
 
 0.752
Isop_1853
DnaK-related protein; COGs: COG0443 Molecular chaperone; InterPro IPR001023: IPR018181; KEGG: sfu:Sfum_0343 DnaK-related protein; SPTR: DnaK-related protein; PFAM: DNA-K related protein; Hsp70 protein.
  
 
 0.752
Isop_2389
Heat shock protein 70 family protein; COGs: COG0443 Molecular chaperone; InterPro IPR018181; KEGG: mxa:MXAN_5322 heat shock protein 70 family protein; SPTR: Heat shock protein 70 family protein; PFAM: Hsp70 protein.
  
 
 0.752
Isop_3139
Heat shock protein 70; COGs: COG0443 Molecular chaperone; InterPro IPR018181: IPR001023: IPR013126; KEGG: nhl:Nhal_2517 heat shock protein 70; PFAM: Heat shock protein 70; SPTR: Heat shock protein 70; PFAM: Hsp70 protein.
  
 
 0.752
Isop_1960
ATP-dependent Clp protease adaptor protein ClpS; COGs: COG2127 conserved hypothetical protein; InterPro IPR003769; KEGG: rxy:Rxyl_2055 ATP-dependent Clp protease adaptor protein ClpS; PFAM: ATP-dependent Clp protease adaptor protein ClpS; SPTR: ATP-dependent Clp protease adaptor protein ClpS; PFAM: ATP-dependent Clp protease adaptor protein ClpS.
  
 
 0.745
clpP
ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
   
 
 0.694
clpP-2
ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
   
 
 0.694
clpP-3
ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
   
 
 0.694
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.