STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_0972Peptidase M28; COGs: COG2234 aminopeptidase; InterPro IPR007484; KEGG: nde:NIDE3566 putative peptidase; PFAM: peptidase M28; SPTR: Aminopeptidase; PFAM: Peptidase family M28. (462 aa)    
Predicted Functional Partners:
Isop_1654
Peptidase S9B dipeptidylpeptidase IV domain protein; COGs: COG1506 Dipeptidyl aminopeptidase/acylaminoacyl-peptidase; InterPro IPR000834: IPR002469; KEGG: sus:Acid_5302 peptidase S9B dipeptidylpeptidase IV subunit; PFAM: peptidase S9B dipeptidylpeptidase IV domain protein; peptidase M14 carboxypeptidase A; SMART: peptidase M14 carboxypeptidase A; SPTR: Peptidase S9B, dipeptidylpeptidase IV domain protein; PFAM: Prolyl oligopeptidase family; Dipeptidyl peptidase IV (DPP IV) N-terminal region; Zinc carboxypeptidase.
  
    0.664
Isop_2231
COGs: COG0308 Aminopeptidase N; KEGG: rba:RB5627 aminopeptidase; SPTR: Putative aminopeptidase; PFAM: Peptidase family M1.
  
 
 
 0.621
Isop_0088
Peptidase S9B dipeptidylpeptidase IV domain protein; COGs: COG1506 Dipeptidyl aminopeptidase/acylaminoacyl-peptidase; InterPro IPR002469; KEGG: hoh:Hoch_4258 peptidase S9B dipeptidylpeptidase IV domain protein; PFAM: peptidase S9B dipeptidylpeptidase IV domain protein; SPTR: Peptidase S9B dipeptidylpeptidase IV domain protein; PFAM: Prolyl oligopeptidase family; Dipeptidyl peptidase IV (DPP IV) N-terminal region.
  
    0.587
Isop_3003
Peptidase M16 domain protein; COGs: COG0612 Zn-dependent peptidase; InterPro IPR001431: IPR011765: IPR007863; KEGG: rmr:Rmar_0089 peptidase M16 domain protein; PFAM: peptidase M16 domain protein; SPTR: Peptidase M16 domain protein; PFAM: Peptidase M16 inactive domain; Insulinase (Peptidase family M16); Belongs to the peptidase M16 family.
  
     0.559
Isop_0183
WD40-like beta Propeller containing protein; COGs: COG1506 Dipeptidyl aminopeptidase/acylaminoacyl-peptidase; InterPro IPR011659; KEGG: mxa:MXAN_6601 S9C family peptidase; PFAM: WD40-like beta Propeller containing protein; SPTR: Prolyl oligopeptidase family protein; PFAM: Prolyl oligopeptidase family; WD40-like Beta Propeller Repeat.
  
    0.497
Isop_3297
InterPro IPR000834; KEGG: sus:Acid_1533 peptidase M14, carboxypeptidase A; PFAM: peptidase M14 carboxypeptidase A; SPTR: Peptidase M14, carboxypeptidase A; PFAM: Zinc carboxypeptidase.
  
     0.489
Isop_0971
PAS sensor protein; InterPro IPR000014: IPR001789: IPR013767: IPR013656; KEGG: mgm:Mmc1_3367 multi-sensor hybrid histidine kinase; PFAM: PAS fold-4 domain protein; PAS fold domain protein; response regulator receiver; SMART: PAS domain containing protein; response regulator receiver; SPTR: Multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: Response regulator receiver domain; PAS fold; TIGRFAM: PAS domain S-box.
       0.467
Isop_0484
Peptidase M1 membrane alanine aminopeptidase; COGs: COG0308 Aminopeptidase N; InterPro IPR014782: IPR015211; KEGG: amc:MADE_03140 putative cold-active aminopeptidase; secreted using a signal peptide; PFAM: Peptidase M1 membrane alanine aminopeptidase; Leukotriene A4 hydrolase; SPTR: Peptidase M1 membrane alanine aminopeptidase; PFAM: Leukotriene A4 hydrolase, C-terminal; Peptidase family M1.
  
 
 
 0.465
Isop_2467
Protein of unknown function DUF885; COGs: COG4805 conserved hypothetical protein; InterPro IPR010281; KEGG: scl:sce6178 hypothetical protein; PFAM: protein of unknown function DUF885; SPTR: Putative uncharacterized protein; manually curated; PFAM: Bacterial protein of unknown function (DUF885).
  
     0.462
Isop_1893
Acylaminoacyl-peptidase; COGs: COG1506 Dipeptidyl aminopeptidase/acylaminoacyl-peptidase; InterPro IPR011659; KEGG: kko:Kkor_1452 peptidase S9 prolyl oligopeptidase active site domain protein; PFAM: WD40-like beta Propeller containing protein; PRIAM: Acylaminoacyl-peptidase; SPTR: Putative uncharacterized protein; PFAM: Prolyl oligopeptidase family.
  
    0.450
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.