STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Isop_0975Short-chain dehydrogenase/reductase SDR; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198: IPR002347: IPR020904; KEGG: bbt:BBta_3977 putative 2-deoxy-D-gluconate 3-dehydrogenase; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Putative 2-deoxy-D-gluconate 3-dehydrogenase; PFAM: short chain dehydrogenase. (255 aa)    
Predicted Functional Partners:
Isop_3207
6-phosphogluconate dehydrogenase (decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
  
 0.810
Isop_3517
COGs: COG0036 Pentose-5-phosphate-3-epimerase; InterPro IPR000056; KEGG: plm:Plim_0648 ribulose-phosphate 3-epimerase; PFAM: ribulose-phosphate 3-epimerase; PRIAM: Ribulose-phosphate 3-epimerase; SPTR: Ribulose-phosphate 3-epimerase; PFAM: Ribulose-phosphate 3 epimerase family; TIGRFAM: ribulose-phosphate 3-epimerase.
     
 0.806
Isop_3160
COGs: COG0120 Ribose 5-phosphate isomerase; InterPro IPR004788; KEGG: scl:sce1758 ribose-5-phosphate isomerase; PFAM: Ribose 5-phosphate isomerase; PRIAM: Ribose-5-phosphate isomerase; SPTR: Ribose 5-phosphate isomerase (Phosphoriboisomerase A) (PRI); TIGRFAM: ribose 5-phosphate isomerase; PFAM: Ribose 5-phosphate isomerase A (phosphoriboisomerase A); TIGRFAM: ribose 5-phosphate isomerase.
     
  0.800
Isop_0974
Peptidase M20; COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR002933: IPR011650: IPR001261; KEGG: psl:Psta_1795 acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase; PFAM: peptidase M20; peptidase dimerisation domain protein; SPTR: Acetylornithine deacetylase; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: acetylornithine deacetylase (ArgE); acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase.
   
   0.625
Isop_2985
Ankyrin; COGs: COG0666 FOG: Ankyrin repeat; InterPro IPR002110: IPR020683; KEGG: sin:YN1551_2013 ankyrin; PFAM: Ankyrin; SPTR: Ankyrin; PFAM: Ankyrin repeat.
    
 0.539
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 
 0.521
Isop_2748
COGs: COG0183 Acetyl-CoA acetyltransferase; InterProIPR020615: IPR020610: IPR001412: IPR020613: IPR 020616: IPR020617: IPR002155; KEGG: gau:GAU_1289 acetyl-CoA acetyltransferase; PFAM: Thiolase-like; PRIAM: Acetyl-CoA C-acetyltransferase; SPTR: Acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.464
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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