STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Isop_1005Protein of unknown function DUF1464; COGs: COG2441 butyrate kinase; InterPro IPR009927; KEGG: pfu:PF1187 hypothetical protein; PFAM: protein of unknown function DUF1464; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1464). (346 aa)    
Predicted Functional Partners:
Isop_3640
Proton-translocating NADH-quinone oxidoreductase, chain M; COGs: COG1008 NADH:ubiquinone oxidoreductase subunit 4 (chain M); InterPro IPR010227: IPR001750: IPR003918; KEGG: psl:Psta_0731 proton-translocating NADH-quinone oxidoreductase, chain M; PFAM: NADH/Ubiquinone/plastoquinone (complex I); SPTR: Proton-translocating NADH-quinone oxidoreductase, chain M; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M; PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M.
   
 
 0.781
nuoD
NADH dehydrogenase (quinone); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family.
    
 
 0.774
Isop_2646
Dual specificity protein phosphatase; InterPro IPR000387: IPR000340; KEGG: olu:OSTLU_7942 predicted protein; PFAM: Dual specificity protein phosphatase; SPTR: Predicted protein; PFAM: Dual specificity phosphatase, catalytic domain.
  
     0.753
Isop_3202
Hypothetical protein; KEGG: ttu:TERTU_3103 putative type I phosphodiesterase/nucleotide pyrophosphatase; SPTR: Putative type I phosphodiesterase/nucleotide pyrophosphatase; PFAM: Type I phosphodiesterase / nucleotide pyrophosphatase.
  
     0.739
Isop_0601
KEGG: sus:Acid_4318 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.705
Isop_0798
NADH/Ubiquinone/plastoquinone (complex I); COGs: COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter MnhA subunit; InterPro IPR003916: IPR018393: IPR001516: IPR001750; KEGG: bra:BRADO2284 putative NADH dehydrogenase (NADH quinone oxidoreductase)(nuoL3-like); PFAM: NADH/Ubiquinone/plastoquinone (complex I); NADH-Ubiquinone oxidoreductase (complex I) chain 5/L domain protein; SPTR: Putative NADH dehydrogenase (NADH quinone oxidoreductase)(NuoL3-like); PFAM: NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; NADH-Ubiquinone/plastoquinone [...]
    
 
 0.691
Isop_3641
Proton-translocating NADH-quinone oxidoreductase, chain L; COGs: COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter MnhA subunit; InterProIPR001516: IPR001750: IPR003945: IPR003916: IPR 018393; KEGG: plm:Plim_3868 proton-translocating NADH-quinone oxidoreductase, chain L; PFAM: NADH/Ubiquinone/plastoquinone (complex I); NADH-Ubiquinone oxidoreductase (complex I) chain 5/L domain protein; SPTR: Proton-translocating NADH-quinone oxidoreductase, chain L; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain L; PFAM: NADH-Ubiquinone/plastoq [...]
    
 
 0.691
Isop_0604
phospholipase/Carboxylesterase; InterPro IPR003140; KEGG: sus:Acid_1148 putative esterase; PFAM: phospholipase/Carboxylesterase; SPTR: Putative esterase; PFAM: Phospholipase/Carboxylesterase.
  
     0.687
Isop_2419
YD repeat protein; COGs: COG3209 Rhs family protein; InterPro IPR003587: IPR006530: IPR006141; KEGG: plm:Plim_1036 AmoP; PFAM: YD repeat-containing protein; SMART: Hedgehog/intein hint domain protein; SPTR: AmoP; TIGRFAM: YD repeat protein; PFAM: RHS Repeat; Protein of unknown function (DUF1557); TIGRFAM: RHS repeat-associated core domain; YD repeat (two copies).
  
     0.687
Isop_1833
CRISPR-associated protein, GSU0054; InterPro IPR019089; KEGG: hoh:Hoch_4849 hypothetical protein; PFAM: CRISPR-associated protein, GSU0054; SPTR: Putative uncharacterized protein; PFAM: CRISPR-associated protein, GSU0054 family (Cas_GSU0054); TIGRFAM: CRISPR-associated protein, GSU0054 family.
  
     0.681
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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