STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Isop_1019PfkB domain protein; COGs: COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); InterPro IPR011611: IPR002173; KEGG: sth:STH1246 tagatose-6-phosphate kinase; PFAM: PfkB domain protein; SPTR: Tagatose-6-phosphate kinase; PFAM: pfkB family carbohydrate kinase; TIGRFAM: hexose kinase, 1-phosphofructokinase family. (330 aa)    
Predicted Functional Partners:
Isop_0943
COGs: COG3684 Tagatose-1 6-bisphosphate aldolase; InterPro IPR002915; KEGG: deb:DehaBAV1_1156 tagatose 1,6-diphosphate aldolase; PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; PRIAM: Tagatose-bisphosphate aldolase; SPTR: Tagatose-bisphosphate aldolase; PFAM: DeoC/LacD family aldolase; TIGRFAM: tagatose 1,6-diphosphate aldolase.
 
 
 0.945
Isop_1623
Transcriptional regulator, DeoR family; COGs: COG1349 Transcriptional regulators of sugar metabolism; InterPro IPR001034: IPR018356: IPR014036; KEGG: psl:Psta_3278 transcriptional regulator, DeoR family; PFAM: regulatory protein DeoR; SMART: regulatory protein DeoR; SPTR: Transcriptional regulator, DeoR family; PFAM: Bacterial regulatory proteins, deoR family; DeoR-like helix-turn-helix domain.
 
  
 0.905
Isop_1109
PTS IIA-like nitrogen-regulatory protein PtsN; COGs: COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); InterPro IPR002178; KEGG: plm:Plim_0361 phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; SPTR: Phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; PFAM: Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2.
 
  
 0.864
Isop_0370
PTS IIA-like nitrogen-regulatory protein PtsN; COGs: COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); InterPro IPR000551: IPR010093: IPR002178; KEGG: gur:Gura_0893 putative PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: regulatory protein MerR; SPTR: Putative PTS IIA-like nitrogen-regulatory protein PtsN; TIGRFAM: DNA binding domain protein, excisionase family; PFAM: Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; TIGRFAM: DNA binding domain, excisionase family.
  
  
 0.678
Isop_0677
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
  
 0.583
Isop_1108
COGs: COG1925 Phosphotransferase system HPr-related protein; InterPro IPR000032: IPR005698; KEGG: gau:GAU_1482 phosphocarrier protein HPr; PFAM: phosphoryl transfer system HPr; SPTR: Phosphocarrier protein HPr; TIGRFAM: phosphocarrier, HPr family; PFAM: PTS HPr component phosphorylation site; TIGRFAM: Phosphotransferase System HPr (HPr) Family.
 
  
 0.574
Isop_1107
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
  
 0.562
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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