Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Isop_1051COGs: COG1680 Beta-lactamase class C and other penicillin binding protein; InterPro IPR001466; KEGG: sus:Acid_4848 beta-lactamase; PFAM: beta-lactamase; SPTR: Beta-lactamase; PFAM: Beta-lactamase. (378 aa)    
Predicted Functional Partners:
Isop_2258
Amidohydrolase 3; COGs: COG1574 metal-dependent hydrolase with the TIM-barrel fold; InterPro IPR013108; KEGG: scl:sce3068 putative secreted protein; PFAM: Amidohydrolase 3; SPTR: Putative lipoprotein; PFAM: Amidohydrolase family.
 
     0.524
Isop_1530
COGs: COG0657 Esterase/lipase; KEGG: psl:Psta_2974 alpha/beta hydrolase fold-3 domain protein; SPTR: Alpha/beta hydrolase fold-3 domain protein; PFAM: alpha/beta hydrolase fold.
 
   
 0.453
Isop_2508
Hypothetical protein; COGs: COG1506 Dipeptidyl aminopeptidase/acylaminoacyl-peptidase; KEGG: psl:Psta_1537 peptidase S9 prolyl oligopeptidase active site domain protein; SPTR: Alpha/beta hydrolase domain-containing protein; PFAM: alpha/beta hydrolase fold.
  
     0.419
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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