Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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Score
Isop_1054COGs: COG3836 2 4-dihydroxyhept-2-ene-1 7-dioic acid aldolase; InterPro IPR005000; KEGG: plm:Plim_3155 2-dehydro-3-deoxyglucarate aldolase; PFAM: HpcH/HpaI aldolase; PRIAM: 4-hydroxy-2-oxovalerate aldolase; SPTR: 2-dehydro-3-deoxyglucarate aldolase; PFAM: HpcH/HpaI aldolase/citrate lyase family; Belongs to the HpcH/HpaI aldolase family. (267 aa)    
Predicted Functional Partners:
Isop_3653
HpcH/HpaI aldolase; COGs: COG3836 2 4-dihydroxyhept-2-ene-1 7-dioic acid aldolase; InterPro IPR005000; KEGG: psl:Psta_0796 HpcH/HpaI aldolase; PFAM: HpcH/HpaI aldolase; SPTR: HpcH/HpaI aldolase; PFAM: HpcH/HpaI aldolase/citrate lyase family; Belongs to the HpcH/HpaI aldolase family.
  
  
 
0.928
Isop_2885
Succinate semialdehyde dehydrogenase; COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR016160: IPR015590; KEGG: bts:Btus_0370 succinic semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: Succinic semialdehyde dehydrogenase; PFAM: Aldehyde dehydrogenase family; TIGRFAM: succinate-semialdehyde dehydrogenase.
  
 
 0.904
Isop_1397
COGs: COG2721 Altronate dehydratase; InterPro IPR013974: IPR007392; KEGG: kra:Krad_0582 altronate dehydratase; PFAM: D-galactarate dehydratase/Altronate hydrolase domain protein; SAF domain protein; PRIAM: Galactarate dehydratase; SPTR: Altronate dehydratase; PFAM: SAF domain; D-galactarate dehydratase / Altronate hydrolase, C terminus.
 
 
  0.683
Isop_2533
Intradiol ring-cleavage dioxygenase; COGs: COG3485 Protocatechuate 3 4-dioxygenase beta subunit; InterPro IPR017909: IPR000627: IPR006311; KEGG: psl:Psta_3106 intradiol ring-cleavage dioxygenase; PFAM: intradiol ring-cleavage dioxygenase; SPTR: Intradiol ring-cleavage dioxygenase; PFAM: Dioxygenase.
  
     0.468
Isop_0489
Rieske (2Fe-2S) iron-sulfur domain protein; COGs: COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenase large terminal subunit; InterPro IPR017941: IPR001663; KEGG: chl:Chy400_2532 Rieske (2Fe-2S) domain protein; PFAM: Rieske [2Fe-2S] iron-sulphur domain; SPTR: Rieske (2Fe-2S) domain protein; PFAM: Rieske [2Fe-2S] domain.
  
   
 0.455
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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