STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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Isop_1055Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. (194 aa)    
Predicted Functional Partners:
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
 
 
  0.917
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
    
  0.905
cmk
COGs: COG0283 Cytidylate kinase; InterPro IPR003136: IPR011994; KEGG: alv:Alvin_1646 cytidylate kinase; PFAM: cytidylate kinase region; SPTR: Cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: Cytidylate kinase; TIGRFAM: cytidylate kinase.
    
  0.904
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
  0.904
pyrR
Uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
    
  0.902
surE
5'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
  0.900
Isop_0905
NUDIX hydrolase; InterPro IPR020476: IPR000086: IPR020084; KEGG: hut:Huta_0878 NUDIX hydrolase; PFAM: NUDIX hydrolase; SPTR: NUDIX hydrolase; PFAM: NUDIX domain; Belongs to the Nudix hydrolase family.
   
 
  0.900
Isop_1215
COGs: COG0035 Uracil phosphoribosyltransferase; InterPro IPR005765: IPR000836; KEGG: ttr:Tter_1755 uracil phosphoribosyltransferase; PFAM: phosphoribosyltransferase; SPTR: Uracil phosphoribosyltransferase; TIGRFAM: uracil phosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: uracil phosphoribosyltransferase; Belongs to the UPRTase family.
     
  0.900
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
     
  0.900
pyrF
COGs: COG0284 Orotidine-5'-phosphate decarboxylase; InterPro IPR018089: IPR011995: IPR001754; KEGG: psl:Psta_1002 orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; PRIAM: Orotidine-5'-phosphate decarboxylase; SPTR: Orotidine 5'-phosphate decarboxylase; TIGRFAM: orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase / HUMPS family; TIGRFAM: orotidine 5'-phosphate decarboxylase, subfamily 2; Belongs to the OMP decarboxylase family. Type 2 subfamily.
     
  0.900
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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