Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Isop_1063Periplasmic solute binding protein; COGs: COG0803 ABC-type metal ion transport system periplasmic component/surface adhesin; InterPro IPR006311: IPR006127: IPR006128: IPR006129; KEGG: sth:STH1506 ABC transporter permease protein; PFAM: periplasmic solute binding protein; SPTR: ABC transporter permease protein; PFAM: Periplasmic solute binding protein family; Belongs to the bacterial solute-binding protein 9 family. (345 aa)    
Predicted Functional Partners:
Isop_1060
ABC-3 protein; COGs: COG1108 ABC-type Mn2+/Zn2+ transport systems permease components; InterPro IPR001367: IPR001626; KEGG: psl:Psta_4677 ABC-3 protein; PFAM: ABC-3 protein; iron dependent repressor; SMART: iron dependent repressor; SPTR: ABC-3 protein; PFAM: ABC 3 transport family; Iron dependent repressor, metal binding and dimerisation domain.
 
 0.998
Isop_1062
ABC transporter related protein; COGs: COG1121 ABC-type Mn/Zn transport systems ATPase component; InterPro IPR003593: IPR003439: IPR017871; KEGG: psl:Psta_4675 ABC transporter related protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related protein; PFAM: ABC transporter.
 
 
 0.998
Isop_1061
ABC-3 protein; COGs: COG1108 ABC-type Mn2+/Zn2+ transport systems permease components; InterPro IPR001626; KEGG: psl:Psta_4676 ABC-3 protein; PFAM: ABC-3 protein; SPTR: ABC-3 protein; PFAM: ABC 3 transport family.
 
 0.996
rpmB
Ribosomal protein L28; InterPro IPR001383; KEGG: psl:Psta_4214 ribosomal protein L28; PFAM: ribosomal protein L28; SPTR: 50S ribosomal protein L28; TIGRFAM: ribosomal protein L28; PFAM: Ribosomal L28 family; TIGRFAM: ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family.
  
  
 0.658
rpsZ
SSU ribosomal protein S14P; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
  
  
 0.656
Isop_1212
Cobalamin synthesis protein P47K; COGs: COG0523 Putative GTPase (G3E family); InterPro IPR003495: IPR011629; KEGG: rme:Rmet_1098 cobalamin synthesis protein P47K; PFAM: cobalamin synthesis protein P47K; cobalamin synthesis CobW domain protein; SPTR: Cobalamin synthesis protein/P47K; PFAM: Cobalamin synthesis protein cobW C-terminal domain; CobW/HypB/UreG, nucleotide-binding domain.
  
  
 0.649
Isop_3242
Cobalamin synthesis protein P47K; COGs: COG0523 Putative GTPase (G3E family); InterPro IPR003495: IPR011629; KEGG: rrs:RoseRS_3105 cobalamin synthesis protein, P47K; PFAM: cobalamin synthesis protein P47K; cobalamin synthesis CobW domain protein; SPTR: Cobalamin synthesis protein, P47K; PFAM: CobW/HypB/UreG, nucleotide-binding domain; Cobalamin synthesis protein cobW C-terminal domain.
  
  
 0.649
Isop_1644
PDZ/DHR/GLGF domain protein; InterPro IPR001478; KEGG: rmr:Rmar_0910 glycosyl hydrolase BNR repeat-containing protein; PFAM: PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; SPTR: Glycosyl hydrolase BNR repeat-containing protein; PFAM: BNR/Asp-box repeat.
  
  
 0.471
Isop_1059
COGs: COG3597 Uncharacterized protein/domain associated with GTPase; KEGG: alv:Alvin_1745 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: GTPase of unknown function; Domain of unknown function (DUF697).
       0.454
ribA
GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family.
     
 0.422
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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