Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Isop_1096Homospermidine synthase (spermidine-specific); COGs: COG1899 Deoxyhypusine synthase; InterPro IPR002773; KEGG: aca:ACP_1729 deoxyhypusine synthase-like protein; PFAM: deoxyhypusine synthase; SPTR: Deoxyhypusine synthase family protein; PFAM: Deoxyhypusine synthase; TIGRFAM: deoxyhypusine synthase; Belongs to the deoxyhypusine synthase family. (356 aa)    
Predicted Functional Partners:
efp
Translation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
   
 0.829
Isop_2851
COGs: COG0231 Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A); InterProIPR011768: IPR013185: IPR001059: IPR015365: IPR 020599; KEGG: rba:RB12577 translation elongation factor EF-P; PFAM: Elongation factor P; Elongation factor P/YeiP protein; Elongation factor KOW-like domain-containing protein; SPTR: Translation elongation factor EF-P; TIGRFAM: translation elongation factor P; PFAM: Elongation factor P, C-terminal; Elongation factor P (EF-P) KOW-like domain; Elongation factor P (EF-P) OB domain; TIGRFAM: translation elongation factor P.
   
 0.829
Isop_3291
Arginine decarboxylase; COGs: COG1945 conserved hypothetical protein; InterPro IPR002724; KEGG: aca:ACP_1744 pyruvoyl-dependent arginine decarboxylase; PFAM: Pyruvoyl-dependent arginine decarboxylase; PRIAM: Arginine decarboxylase; SPTR: Arginine decarboxylase, pyruvoyl-dependent; TIGRFAM: arginine decarboxylase, pyruvoyl-dependent; PFAM: Pyruvoyl-dependent arginine decarboxylase (PvlArgDC); TIGRFAM: arginine decarboxylase, pyruvoyl-dependent.
 
   
 0.660
rplF
LSU ribosomal protein L6P; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
   
   0.624
Isop_1097
InterPro IPR014346: IPR003675; KEGG: amr:AM1_1967 CAAX prenyl protease-related protein, putative; PFAM: Abortive infection protein; SPTR: Caax prenyl protease-related protein, putative; TIGRFAM: CAAX prenyl protease-related protein; PFAM: CAAX amino terminal protease family; TIGRFAM: CAAX prenyl protease-related protein.
       0.566
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
    0.414
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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