Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_109840-residue YVTN family beta-propeller repeat protein; COGs: COG3391 conserved hypothetical protein; InterPro IPR011964: IPR007312; KEGG: sus:Acid_4558 YVTN beta-propeller repeat-containing protein; PFAM: phosphoesterase; SPTR: 40-residue YVTN family beta-propeller repeat protein; TIGRFAM: 40-residue YVTN family beta-propeller repeat protein; PFAM: Phosphoesterase family; 3-carboxy-cis,cis-muconate lactonizing enzyme; TIGRFAM: 40-residue YVTN family beta-propeller repeat. (896 aa)    
Predicted Functional Partners:
Isop_3281
InterPro IPR012577; KEGG: psl:Psta_4030 NIPSNAP family containing protein; PFAM: NIPSNAP family containing protein; SPTR: NIPSNAP family containing protein; PFAM: NIPSNAP.
  
     0.467
Isop_0278
Acetyl xylan esterase; InterPro IPR000834: IPR008391; KEGG: psl:Psta_2878 hypothetical protein; PFAM: Acetyl xylan esterase; SPTR: Putative uncharacterized protein; PFAM: Acetyl xylan esterase (AXE1).
  
     0.461
Isop_1097
InterPro IPR014346: IPR003675; KEGG: amr:AM1_1967 CAAX prenyl protease-related protein, putative; PFAM: Abortive infection protein; SPTR: Caax prenyl protease-related protein, putative; TIGRFAM: CAAX prenyl protease-related protein; PFAM: CAAX amino terminal protease family; TIGRFAM: CAAX prenyl protease-related protein.
       0.456
Isop_1644
PDZ/DHR/GLGF domain protein; InterPro IPR001478; KEGG: rmr:Rmar_0910 glycosyl hydrolase BNR repeat-containing protein; PFAM: PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; SPTR: Glycosyl hydrolase BNR repeat-containing protein; PFAM: BNR/Asp-box repeat.
 
    0.454
Isop_1099
Efflux transporter, RND family, MFP subunit; COGs: COG0845 Membrane-fusion protein; InterPro IPR006143; KEGG: nhl:Nhal_0824 efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; SPTR: Efflux transporter, RND family, MFP subunit; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: HlyD family secretion protein; TIGRFAM: RND family efflux transporter, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
    0.452
Isop_2013
COGs: COG3386 Gluconolactonase; InterPro IPR000801: IPR013658: IPR005511; KEGG: plm:Plim_2162 SMP-30/gluconolaconase/LRE domain protein; PFAM: SMP-30/Gluconolaconase/LRE-like region-containing protein; esterase; SPTR: SMP-30/Gluconolaconase/LRE domain protein; PFAM: SMP-30/Gluconolaconase/LRE-like region; Putative esterase.
 
    0.449
Isop_1100
Acriflavin resistance protein; COGs: COG0841 Cation/multidrug efflux pump; InterPro IPR001036; KEGG: nhl:Nhal_0822 acriflavin resistance protein; PFAM: acriflavin resistance protein; SPTR: Acriflavin resistance protein; PFAM: AcrB/AcrD/AcrF family; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
       0.443
Isop_3537
InterPro IPR013222; KEGG: psl:Psta_2909 glycosyl hydrolase family 98 putative carbohydrate binding module; PFAM: Glycosyl hydrolase family 98 putative carbohydrate binding module; SMART: Glycosyl hydrolase family 98 putative carbohydrate binding module; SPTR: Putative uncharacterized protein; PFAM: NPCBM/NEW2 domain.
  
    0.408
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
Server load: medium (58%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.